Raivio group discovers new genetic diseases that affect growth and development and models their mechanisms with human pluripotent stem cells and mice. In addition, the group develops new diagnostic and treatment strategies to patients with delayed puberty.
The main techniques employed are
- Genomic editing of human pluripotent stem cells with CRISPR/CAS9
- Stem cell maintenance and differentiation
- FACS, WB, IF, qPCR, ELISA, NGS, etc.