Kaprio group/twin study
Department of Public Health
Institute for Molecular Medicine Finland (FIMM)
P.O. Box 20, 00014 University of Helsinki, Finland
Jaakko Kaprio obtained his M.D. degree in 1976 and his Ph.D. in 1984 from the University of Helsinki. He has trained abroad at the University of Southern California, Indiana University and University of Michigan in 1987-1989. During 2007-2011 he was the Director of the Academy of Finland Centre of Excellence in Complex Disease Genetics. During 2013-2017 Kaprio held a Professorship of the Academy of Finland.
He has been in a key role in collecting several Finnish twin cohorts for the University of Helsinki and in planning the long-term follow-up studies of the twins.
Professor Kaprio’s central research interests have been in the study of substance use and addictions, nicotine dependence in particular. He has authored and co-authored > 1100 scientific articles throughout his career, supervised > 50 PhD students, and has received multiple awards.
Elissar Azzi is a doctoral researcher in the Kaprio group. She holds a master’s degree in biological sciences, with a focus on neuroendocrinology.
Her current research examines the long-term impact of stressful life events on health outcomes, particularly cancer, using data from the Finnish Twin Cohort. She is specifically interested in the role of inflammation in mediating the effects of stress on disease susceptibility. Her work also builds on prior experience investigating inflammatory profiles in lung cancer, furthering the understanding of how systemic responses to stress influence disease outcomes across different conditions.
Sabrina Belgasem works as a clinical research nurse in the Kaprio group.
Kauko Heikkilä works as a consult in Group Kaprio. Task as a consult of group Kaprio is to make data more usable by sharing silent information. I try to solve data usability problems when emerging, making details more identifiable for quicker access. All data metadata can be delivered as an Excel file with dataset information with variables and their labels (hopefully soon a better version could be delivered), or they can also be input to a menu driven program some day. Another task is to finalize the dissertation, hopefully latest before June 2020.
Docent
Sarah Niemi de Paiva (MPH, Epidemiology – in progress) is a graduate student at the University of North Carolina at Chapel Hill, studying epidemiology.
She is currently a research assistant in the Kaprio Group, investigating intergenerational health outcomes and behavioral risk factors using twin study data. Her work focuses on the epidemiology of chronic diseases, with particular interest in perinatal health and smoking, alcohol use, and obesity.
Hilla Ruotsalainen received her MSc in Biomedicine (2023) and is currently a doctoral researcher in the Kaprio group. In addition, she is completing a second Master's degree in Microbiology at the University of Helsinki.
Her PhD research focuses on the identification of novel biomarkers associated with chronic pain conditions. She is especially interested in proteomics as well as gut microbiome changes.
Alongside her PhD and microbiology studies, she also assists with clinical research activities within the Kaprio group.
Stephanie broadly seeks to understand the causes and consequences of substance use and psychopathology, from risk factors like impulsivity and permissive environments to outcomes like substance dependence. She aims to understand why people use substances, what effect it has on their lives, and how we can intervene or prevent substance-related problems. She uses sophisticated study designs and longitudinal twin data to hone in on specific pathways to understand how genes and the environment lead to substance use, addiction, and related psychosocial phenomena.
Stephanie Zellers