People

Set fire to all your maps, forget how it's always been. We are explorers of the "cell", learning to dream again. (adapted from John M. Green)
Leonardo Almeida-Souza, PI

I was born in Brasília, Brazil. I graduated in Biology at the Universidade Federal de São Carlos (UFSCar) and obtained my masters at the Universidade de São Paulo (USP).

For my PhD, I moved to the Flemish Institute of Biotechnology (VIB) in Antwerp, Belgium to study the cellular and biochemical effects of mutations in small heat shock proteins causing Charcot-Marie-Tooth disease.

After a short postdoc in Antwerp, I moved to the MRC Laboratory of Molecular Biology in Cambridge, UK as an EMBO fellow to study endocytosis. My postdoctoral work revealed that the protein FCHSD2 is a major activator of actin polymerisation during Clathrin-Mediated Endocytosis (). I used cell biology, biochemistry and structural biology to reveal multiple aspects of the biology of this protein such as the structural details of its recruitment to endocytic sites, its molecular mechanism of actin polymerisation activation and its unique localisation at the base of clathrin coated pits.

In late 2019, I started my lab at the Helsinki Institute of Life Sciences () as an assistant professor in Cell Biology and in 2021, I became an Academy of Finland Research Fellow. Our research group is located at the Institute of Biotechnology, a leading Finnish research centre hosting  various groups studying biological processes from molecules to organisms. Importantly, we have access to many that enable us to tackle our research questions using various state-of-the-art techniques.

I still enjoy doing experiments and to be directly involved in most projects, when possible. I am the code-monkey of the group and I developed many of the image analysis pipelines used in the lab. Recently, I got involved in the designing of synthetic binders and to facilitate the usage of these tools, I developed a to pre-screen targets. 

Outside the lab I enjoy spending time with my two kids and lovely wife. I am also an enthusiast of woodwork. Building wood furniture is a great way to relax.

An-Sofie Lenaerts, Lab manager

 

 

An-Sofie is from Belgium and as our lab manager, she is responsible for keeping everything running smoothly in the lab.

She is also our CRISPR/Cas9 expert. Before joining us, An-Sofie was the manager of the BRC hIPSC core facility in Cambridge, UK. There, she developed protocols for the efficient genetic engineering of stem cells. She applies her expertise in our lab to generate multiple knock in and knockout cell lines.

More recently, she has also spearheaded the development of a .

Laura Hakanpää, Postdoc

Laura is from Finland.  Her PhD work studied how endothelial cell growth factors and integrin adhesion molecules regulate vascular barriers.

Laura joined our lab in June 2020. Laura studies the relationship between reticular adhesions and the endocytic machinery. In our latest paper, she has made on this topic. Now, Laura is diving deep into the biology of these structures in cancer. 

In her free time Laura writes popularising science articles, learns to play the bass, dances ballet and walks her labrador Hilla.

Seyda Culfa, PhD student

Seyda is from Turkey. She joined our lab in October 2022.

For her PhD, Seyda is studying the role of a novel septin interacting protein in cell migration and cancer.

 

Neža Leskovar, Research assistant (In collaboration with Claudius Kratochwil)

Neza is from Slovenia. She joined our lab in March 2024 for a HiLIFE internship and stayed for her master's thesis. 

Neza is combining her expertise in cell biology and biochemistry to develop technologies to enrich and culture pigment cells from Cichlid fish skin. 

This project is being done in collaboration with the lab of .

 

Alejandro Henar-Izquierdo, Master's student

Alex is from Spain. He joined our lab in September 2025 in an internship which turned into Master's thesis.

Alex is studying the interactome of reticular adhesions. He will stay in the lab for a PhD from September 2026 onwards.

 

Aatu Ruohonen, Master's student

Aatu is from Finland. He joined our lab in August 2025 for an internship and he is now doing his Master's thesis.

Aatu is comparing the results of a large compound screen we performed with the results obtained using computational AI-tools.

 

Marta Lopez, Erasmus student

Marta is from Spain. She joined our lab in Feb 2026 for an Erasmus Internship.

Marta is helping us to understand how post-translational modifications in integrin β5 regulate reticular adhesions.

 

Josua Mayr, Internship

Josua is from Austria. He joined our lab in the Autumn of 2024 as an Erasmus student and came back to Helsinki for his Master's degree and is currently on an internship in our lab since March 2026.

Josua is using his skills as an (now used for microscopy) to help us to visualize reticular adhesions in vivo.

 

Veera Pienimäki, Internship

Veera is in from Finland. She joined our lab in March 2026 for a short internship on machine learning.

Veera is using state-of-the-art image analysis tools to train models capable of measuring various cellular structures.

 

Open positions

 

 

Are you interested in joining us?

We are always looking for enthusiastic people! Drop us a line to check for possibilities.

 

Alumni

Panagiotis (Panos) Lilis, Erasmus Student - Sept 2021 to Dec 2021

Anastasiia Avdeeva, EDUFI Scholarship - Feb 2021 to Jan 2022

Tai Arima, Master's student - Nov 2021 to October 2022

Kirika Karppinen, Undergrad student - Jun 2022 to Jul 2022

Emma Tobarra Lopez, Erasmus Student - Feb 2023 to Jun 2023

Amr Abouelezz, Postdoc - August 2020 to July 2023

Mohammed Quadir, Master's student - September 2023 to January 2024

Narjes Zeinoddin, Master's student -> Research Assistant - Feb 2020 to March 2024

Jekaterina Kristal, Postdoc - Mar 2023 to Feb 2025

Diana Vaskiv, HiLIFE internship - Mar 2024 to May 2024

Josua Mayr, Erasmus student - Sep 2024 to Dec 24 

Sakshi Kumari, internship - Jun 2025 to October 2025

Hassan Yassine, Internship - Mar 2026 to May 2026