New sequencing instruments

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We have purchased new sequencing instruments

Short read sequencer AVITI (Element Biosciences) was delivered and installed in November 2023.

It has industry-leading accuracy: >90% >Q30
Avidity Sequencing employs rolling circle amplification (RCA) to minimize common amplification errors.
- No PCR error propagation
- Negligible index hopping
- Low duplication rates
- Low AT/GC bias

Long read sequencer Revio (Pacific Biosicence, PacBio) was delivered in end of 2023 and installed in January 2024.

Replacing PacBio Sequel II instrument
15x increase in HiFi long read throughput compared to Sequel II
HiFi sequencing provides
- small and structural variants
- repeat extensions
- methylation
- haplotype phasing

Long read sequencer Promethion-2-Solo (Oxford Nanopore) was acquired in spring 2023.

Instrument is used in-house
- high molecular weight DNA sequencing
- direct RNA sequencing

New instruments and training