New sequencing instruments

We have purchased new sequencing instruments
 

Short read sequencer AVITI (Element Biosciences) was delivered and installed in November 2023. 
 

• It has industry-leading accuracy: >90% >Q30
• Avidity Sequencing employs rolling circle amplification (RCA) to minimize common amplification errors.
  • No PCR error propagation
  • Negligible index hopping
  • Low duplication rates
  • Low AT/GC bias

• https://www.elementbiosciences.com/

   

Long read sequencer Revio (Pacific Biosicence, PacBio) was delivered in end of 2023 and installed in January 2024. 

• Replacing PacBio Sequel II instrument
• 15x increase in HiFi long read throughput compared to Sequel II
• HiFi sequencing provides
  • small and structural variants
  • repeat extensions
  • methylation
  • haplotype phasing  

• https://www.pacb.com/

   

Long read sequencer Promethion-2-Solo (Oxford Nanopore) was acquired in spring 2023.

• Instrument is used in-house
  • high molecular weight DNA sequencing
  • direct RNA sequencing
  • https://nanoporetech.com/