Doctoral dissertations supervised/co-supervised by/carried out in collaboration with the researchers at the Department of Clinical Pharmacology, University of Helsinki.
- Teemu Kantola, Effects of itraconazole and some other CYP3A4 inhibitors on the pharmacokinetics of HMG-CoA reductase inhibitors.
- Vilja Palkama, Studies on drug interactions between CYP3A4 inhibitors and anaesthetic drugs.
- Kirsti Villikka, Studies on drug interactions caused by rifampicin and dexamethasone in humans.
- Tommi Lamberg, Effects of inhibition and induction of CYP3A4 on the pharmacokinetics and pharmacodynamics of buspirone.
- Mirja Hämäläinen, L: Optimal drug treatment of recurrent headaches and migraine in children – a clinical and pharmacological study.
- Kirsi-Maija Kaukonen, Studies on the effects of a CYP3A4-inhibitor, itraconazole, on the pharmacokinetics and pharmacodynamcis of cardiovascular drugs.
- Seppo Kähkönen, Pharmacodynamic and pharmacokinetic aspects of propranolol, verapamil and isosorbide dinitrate during alcohol withdrawal.
- Eeva Lukkari, Clinical pharmacology of oxybutynin, with special reference to pharmacokinetics and interaction.
- Reijo Laaksonen, The effect of HMG-CoA reductase inhibitor treatment on serum and skeletal muscle ubiquinone.
- Jouni Ahonen, Studies on CYP3A mediated drug interactions in anaesthesiology.
- Ari Illi, Inhibition of catechol-O-methyltransferase by entacapone: Effects on haemodynamics and catecholamine metabolism and interactions with drugs interfering with catecholamine disposition.
- Harri Luurila, Effect of erythromycin on the pharmacokinetics and pharmacodynamics of hypnotics.
- Anu Varhe, Interactions of triazolam with inhibitors of CYP3A enzymes.
- Janne Backman, Effects of drugs inhabiting and inducing CYP3A enzymes on the pharmacokinetics and pharmacodynamics of oral midazolam.
- Riitta Tokola, Studies on drug absorption and efficacy in migraine attacks.
- Kalle Hoppu, Paediatric clinical pharmacology of trimethoprim.
- Eero Tiula, Effect of renal diseases on serum protein binding of drugs.
- Klaus Olkkola, Factors affecting the antidotal efficacy of oral activated charcoal.
- Jaakko-Juhani Himberg, Optimization and validation of gas-chromatographic drug assays for pharmacokinetic studies.
- Sirkka Elfving, Studies on the naturally occurring goitrogen 5-vinyl-2-thiooxazolidone – metabolism and antithyroid effect in the rat.