Montrose K, Lac DT, Burnetti AJ, Tong K, Bozdag GO, Hukkanen M, Ratcliff WC, Saarikangas J. Proteostatic tuning underpins the evolution of novel multicellular traits.
Carabalona A, Kallo H, Gonzalez M, Andriichuk L, Elomaa E, Molinari F, Fragkou C, Lappalainen P, Wessels MW, Saarikangas J, Rivera C (2024) Identification of novel microcephaly-linked protein ABBA that mediates cortical progenitor cell division and corticogenesis through NEDD9-RhoA.
Paukštytė J, López Cabezas RM, Feng Y, Tong K, Schynder D, Elomaa E, Gregorova P, Doudin M, Särkkä M, Sarameri J, Lippi A, Vihinen H, Juutila J, Nieminen A, Törönen P, Holm L, Jokitalo E, Krisko A, Huiskonen J, Hietakangas V, Picotti P, Barral Y, Saarikangas J. Global analysis of aging-related protein structural changes uncovers enzyme polymerization-based control of longevity.
Senju Y, Mustaq T, Vihinen H, Manninen A, Saarikangas J, Ven K, Engel U, Varjosalo M, Jokitalo E, Lappalainen P. Actin-rich lamellipodia-like protrusions contribute to the integrity of epithelial cell–cell junctions.
Oamen HP, Romero N, Knuckles P, Saarikangas J, Radman-Livaja M, Dong Y and Caudron F. A rare natural lipid induces neuroglobin expression to prevent amyloid oligomers toxicity and retinal neurodegeneration.
Lau Y, Oamen HP, Grogg M, Parfenova I, Saarikangas J, Hannay R, Nichols RA, Hilvert D, Barral Y, and Caudron F. Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell.
van Oosten-Hawle P and Saarikangas J. Special Issue on Cell Stress in Development and Disease.
Montrose K, Lopez-Cabezas RM, Paukstyte J, Saarikangas J. Winter is coming: Regulation of cellular metabolism by enzyme polymerization in dormancy and disease.
Kettunen P, Baumann M, Saarikangas J. Proteiinien laskostumishäiriöt aivojen rappeumasairauksissa.
Sawarkar R, Scherz-Shouval R, Denzel M, Saarikangas J. Chaperoning junior faculty.
Sawarkar R, Scherz-Shouval R, Denzel M, Saarikangas J. Preparing junior faculty for success.
Saarikangas J, Hotulainen P. Hermosolujen synapsien muovautumismekanismit oppimisen, muistin ja aivojen rappeumasairauksien taustalla.
Saarikangas J, Caudron F. Spatial Regulation of Coalesced Protein Assemblies: Lessons from Yeast to Diseases.
Saarikangas J, Caudron F, Prasad R, Moreno DF, Aldea M, Barral Y. ER compartmentalization confines protein aggregation to the aging lineage during asymmetric cell division.
Saarikangas J, Barral Y. Protein aggregation as a mechanism for adaptive cellular responses.
Hotulainen P, Saarikangas J. The initiation of post-synaptic protrusions.
Saarikangas J, Barral Y. Protein aggregates are associated with replicative aging without compromising protein quality control.
Saarikangas J, Kourdougli N, Chazal N, Kuurne J, Senju Y, Mattila PK, Garrett L, Hölter SM, Becker L, Racz I, Hans W, Klopstock T, Wurst W, Zimmer A, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Lappalainen P, Rivera C and Hotulainen P. Dendritic spines are initiated by MIM induced membrane curvature.
Mertz KD, Pathria G, Wagner G, Saarikangas J, Sboner A, Romanov J, Gschaider M, Lenz F, Neumann F, Schreiner W, Nemethova M, Glassmann A, Lappalainen P, Stingl G, Small JV, Fink D, Chin L, Wagner SN. MTSS1 is a Metastasis Driver in a Subset of Human Melanomas.
Maddugoda MP, Stefani C, Gonzalez-Rodriguez D, Saarikangas J, Torrino S, Janel S, Prodon F, Doye A, Goossens PL, Lafont F, Bassereau P, Lappalainen P, Brochard F and Lemichez E. cAMP signaling by anthrax edema toxin induces transendothelial cell tunnels, which are resealed by MIM via Arp2/3-driven actin polymerization.
Saarikangas J and Barral Y. The Emerging Functions of Septins in Metazoans.
Pykalainen A, Boczkowska M, Zhao H, Saarikangas J, Rebowski G, Jansen M, Hakanen J, Koskela E, Peranen J, Vihinen H, Jokitalo E, Salminen M, Ikonen E, Dominguez R, Lappalainen P. Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures.
Saarikangas J, Mattila P.K, Varjosalo M, Bovellan M, Hakanen J, Calzada-Wack J, Tost M, Jennen L, Rathkolb B, Hans W, Horsch M, Hyvönen ME, Perälä N, Fuchs H, Gailus-Durner V, Esposito I, Wolf E, Hrabé de Angelis M, Frilander MJ, Savilahti H, Sariola H, Sainio K, Lehtonen S, Taipale J, Salminen M and Lappalainen P. Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
Saarikangas J, Zhao H and Lappalainen P. Regulation of the Actin Cytoskeleton-Plasma Membrane Interplay by Phosphoinositides.
Saarikangas J, Zhao H, Pykalainen A, Laurinmaki P, Mattila PK, Kinnunen PK, Butcher SJ and Lappalainen P. Molecular mechanisms of membrane deformation by I-BAR domain proteins.
Saarikangas J, Hakanen J, Mattila PK, Grumet M, Salminen M and Lappalainen P. ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension.
Mattila PK, Pykalainen A, Saarikangas J, Paavilainen VO, Vihinen H, Jokitalo E and Lappalainen P. Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanism.