RECENT PUBLICATIONS

▪ Acheva A., Kärki, T., Schaible, N., Krishnan, R. and  Tojkander S. Adipokine leptin co-operates with mechanosensitive Ca2+-channels and triggers actomyosin-mediated motility of breast epithelial cells. Front. Cell Dev. Biol. 2020 doi: 10.3389/fcell.2020.607038

▪ Kärki T, Rajakylä EK, Acheva A, Tojkander S. TRPV6 calcium channel directs homeostasis of the mammary epithelial sheets and controls epithelial mesenchymal transition. Sci Rep. 2020 Sep 7;10(1):14683. doi: 10.1038/s41598-020-71645-z. PMID: 32895467; PMCID: PMC7477193.

▪ Rajakylä K., Lehtimäki J., Acheva A, Schaible N., Lappalainen P., Krishnan. R. and Tojkander S. (2020). Assembly of peripheral actomyosin bundles in epithelial cells is dependent on CaMKK2/AMPK pathway. Cell Reports, 30:4266-4280.e4.

▪ Kumari, R., Jiu, Y., Carman, P.,Tojkander, S. Kogan, K., Varjosalo, M., Gunning, P., Dominguez,  R. and Lappalainen, P. (2020). Tropomodulins control balance between protrusive and contractile structures in migrating cells by stabilizing tropomyosin-decorated actin filaments. Curr Biol. pii: S0960-9822: 31682-3.

▪ Guenther C., Faisal I., Uotila L.M., Asens M.L., Harjunpää H., Savinko T., Öhman T., Yao S., Moser M., Morris S.W., Tojkander S., Fagerholm S.C. (2019). A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation. Front Immunol. 28;10:1138.

▪ Ciuba K., Hawkes W., Tojkander S., Kogan K., Engel U., Iskratsch T., Lappalainen P. (2018). Calponin-3 is critical for coordinated contractility of actin stress fibers. Scientific reports, 8, 17670.

▪ Tojkander S., Ciuba K., Lappalainen P. (2018): CaMKK2 regulates mechanosensitive assembly of contractile actin stress fibers. Cell reports 24, 11-19. *First and corresponding author.

▪ Savinko T., Uotila L.M., Guenther C., Asens M.L., Yao S., Tojkander S., Fagerholm S.C. (2018). Filamin A is required for optimal T cell integrin-mediated force transmission, flow adhesion and T cell trafficking. J Immunol, 200:3109-3116.

▪ Rajakylä K., Krishnan R., Tojkander S. (2017). Analysis of contractility and invasion potential of two canine mammary tumor cell lines. Frontiers: Preclinical Models of Canine Mammary Neoplasia, Frontiers in Vet Sci, vol 4. doi:10.3389/fvets.2017.00149.

▪ Tojkander S, Gateva G, Husain A, Krishnan R, Lappalainen P (2015): Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly. eLife, Dec 10;4. pii: e06126.