Research

The research is coupled to both experiments and applications as our team collaborates with about 50 different experimental teams. The focus of research is on cross-disciplinary problems in the field where the traditional borderlines between physics, chemistry, and computational and medical sciences tend to vanish. The grand objective is to use computational simulations for considerations of phenomena that are relevant to health and disease.

From modeling point of view, we also develop and employ a variety of different techniques to allow studies of complex biomolecular systems over large scales in time and space. Consequently, one of our main objectives is to bridge nanoscale and macroscopic regimes in terms of multiscale modeling.

Concerning larger reseach efforts, our group is a partner in the where research focuses on understanding the function of biological barriers and the causes of their malfunction, as well as correcting these disorders. Our team focuses on simulations and theory, and the teams directed by Johanna Ivaska, Sara Wickström, Pipsa Saharinen and Pekka Lappalainen carry out outstanding experimental life science work.

Furthermore, we are strongly committed to studying lipid-protein interactions and the mechanisms of how lipids modulate protein function in crowded membranes. These are the essence of the ERC Advanced Grant project that was awarded to us by the . This work is continued in the context of neurosciences, cardiovascular diseases, and eye disorders with the support granted by the and the .

An overall perspective of our recent work can be found by considering of our group.