Publications

Peer-reviewed research articles

Conference presentations and posters

  • Somppi S, Törnqvist H, Koskela A, Krause CM, Topál J, Vainio O. 2016. Nasal oxytocin enhances gazing at eyes of smiling humans in domestic dogs. The 5th Canine Science Symposium, Padova, Italy.
  • Kujala MV, Kujala J, Törnqvist H, Vainio O, Parkkonen L. 2016. Dogs’ brain responses to faces and objects measured with non-invasive electroencephalography. 8th European Conference of Comparative Neurobiology, Munich, Germany.
  • Kujala MV, Somppi S, Koskela AM, Törnqvist H, Vainio O, Parkkonen L. 2014. Valence and arousal ratings of dogs and human facial expressions by human observers. The 4rd Canine Science Forum, Lincoln, England.
  • Somppi S, Törnqvist H, Kujala MV, Koskela A, Hänninen L, Krause CM, Vainio O. 2014. Facial expressions modulate scanning pattern in domestic dogs. The 4rd Canine Science Forum, Lincoln, England.
  • Norring M, Somppi S, Törnqvist H, Hänninen L, Vainio O. 2014. Cognition studies refined with pet animals. The 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague, Czech Republic.
  • Somppi S, Törnqvist H, Hänninen L, Krause CM, Vainio O. 2013. How dogs process inverted and familiar faces. The 47th ISAE International Congress, Florianopolis, Brazil.
  • Törnqvist H, Kujala MV, Somppi S, Koskela A, Krause CM, Vainio O. 2013. How dogs and humans observe images of natural social interaction: a comparative eye-tracking study. 3rd Transfer-of-knowledge conference of the Evolution of Comparative Cognition,Vienna, Austria.
  • Kujala MV, Törnqvist H, Somppi S, Hänninen L, Krause CM, Kujala J, Vainio O. 2013. Cognitive brain oscillations associated with visual perception in humans and dogs. 3rd Transfer-of-knowledge conference of the Evolution of Comparative Cognition,Vienna, Austria.
  • Törnqvist H, Kujala MV, Somppi S, Hänninen L, Pastell M, Krause CM, Kujala J, Vainio O. 2012. Visual event-related potentials of dogs recorded with fully non-invasive electroencephalography. The 3rd Canine Science Forum, Barcelona, Spain.
  • Somppi S, Törnqvist H, Hänninen L, Krause CM, Vainio O. 2012. How dogs process familiar and inverted faces, an eye movement study. The 3rd Canine Science Forum, Barcelona, Spain.
  • Somppi S, Törnqvist H, Hänninen L, Krause CM, Vainio O. 2011. How dogs process faces: an eye movement study. The 2nd Transfer-of-knowledge conference of the Evolution of Comparative Cognition, Prague, Czech Republic.
  • Somppi S, Törnqvist H, Hänninen L, Krause CM, Vainio O. 2010. Dogs do look at images – Eye tracking in canine cognition research. The 2nd Canine Science Forum, Vienna, Austria.
  • Somppi S, Malkamäki S, Valros A. 2010. Aggression toward people by rottweiler dogs. The 44th International Congress of the Society for Applied Ethology, Uppsala, Sweden.

Peer-reviewed research articles

Conference presentations and posters

  • Kujala MV, Somppi S, Jokela M, Vainio O, Parkkonen L. 2016. How humans estimate emotions from dog and human faces – Connections to empathy, personality and experience. Animal and Human Emotions, Erice, Sicily, Italy.
  • Kujala MV. 2015. Koiran ja ihmisen sosiaalinen mieli. (finnish) Think Corner, Helsinki, Finland.
  • Kujala MV, Somppi S, Koskela A, Törnqvist H, Vainio O, Parkkonen L. 2014. Valence and arousal ratings of dogs and human facial expressions by human observers. The 4rd Canine Science Forum, Lincoln, England.
  • Kujala MV. 2013. Visual perception of social stimuli in humans and dogs - Why and how to compare processing across species? 2nd BRAHE Symposium, Helsinki, Finland.
  • Kujala MV. 2013. Of dogs and humans: How do humans see social gestures of non-human species? Animal Concepts, Helsinki, Finland.
  • Törnqvist H, Kujala MV, Somppi S, Koskela A, Krause CM, Vainio O. 2013. How dogs and humans observe images of natural social interaction: a comparative eye-tracking study. 3rd Transfer-of-knowledge conference of the Evolution of Comparative Cognition, Vienna, Austria.
  • Kujala MV, Törnqvist H, Somppi S, Hänninen L, Krause CM, Kujala J, Vainio O. 2013. Cognitive brain oscillations associated with visual perception in humans and dogs. 3rd Transfer-of-knowledge conference of the Evolution of Comparative Cognition, Vienna, Austria.
  • Kujala MV. 2013. Mitä aivoissamme tapahtuu kun katsomme koiraa? (finnish) Think Corner, Helsinki, Finland.
  • Kujala MV, Carlson S, Hari R. 2011. Dog experts read social interaction of dogs and humans alike: Expertise-related brain correlates of reading body postures across species. 2nd Transfer-of-knowledge conference of the Evolution of Comparative Cognition, Prague, Czeck Republic.

Peer-reviewed research articles

Conference presentation and posters

  • Telkänranta H, Koskela A, Pierard M, Menor-Campos DJ, Kujala MV, Törnqvist H, Somppi S, Vainio O, Vainionpää M. 2016. Thermal imaging: a non-invasive technique to measure physiological processes linked to emotions. Measuring Animal Emotions workshop, Edinburgh, Scotland.
  • Telkänranta H, Koskela A, Pierard M, Menor-Campos DJ, Kujala MV, Törnqvist H, Somppi S, Vainio O, Vainionpää M. 2016. Infrared thermography as a non-invasive tool for quantifying emotional arousal in rats, dogs and elephants: recent findings and methodological aspects. Animal and Human Emotions, Erice, Sicily, Italy.

Peer-reviewed research articles (since 2000)

Conference presentations and posters (since 2015)

  • Adam M, Huuskonen V, Raekallio MR, Casoni D, Mykkänen AK, Lappalainen AK, Vainio O. Haemodynamic effects of MK-467, a peripherally acting alpha2-adrenoceptor antagonist, in sevoflurane-anaesthetized sheep receiving dexmedetomidine. Association of Veterinary Anaesthetists Autumn Meeting, Berlin, 9-12.11.2017.

  • Huuskonen V, Adam M, Raekallio MR, Mykkänen AK, Casoni D, Lappalainen AK, Vainio O. MK-467, a peripherally acting alpha2-adrenoceptor antagonist, alleviates dexmedetomidine-induced pulmonary changes in sevoflurane-anaesthetised sheep. Association of Veterinary Anaesthetists Autumn Meeting, Berlin, 9-12.11.2017.

  • Turunen H, Raekallio MR, Adam M, Helin H, Nevanperä K, Kallio-Kujala IJ, Honkavaara MJ, Restitutti F, Larenza Menzies MP, Vainio O. The effects of MK-467, a peripheral α₂-adrenergic receptor antagonist, on the plasma drug concentrations and sedation in dogs receiving atipamezole to reverse medetomidine-induced sedation. Association of Veterinary Anaesthetists Autumn Meeting, Berlin, 9-12.11.2017.

  • Kallio-Kujala IJ, Turunen HM, Raekallio MR, Honkavaara J, Salla K, Casoni D, Hautajärvi H, Vainio O. Intramuscular use of a peripherally acting alpha2-adrenoceptor antagonist MK-467 with medetomidine and butorphanol in dogs – a prospective, randomized clinical trial. Association of Veterinary Anaesthetists Autumn Meeting, Berlin, 9-12.11.2017.

  • Tapio H, Raekallio M, Mykkänen A, Mama K, Mendez Angulo JL, Hautajärvi H, Vainio O. Effects of MK-467 and hyoscine on cardiovascular and gastrointestinal changes induced by detomidine in horses. Annual Scientific Meeting of ECVS (European College of Veterinary Surgeons),  Edinburgh, UK, 13.-15.7.2017. (poster)

  • Keskitalo TK, Adam M, Raekallio MR, Vainio OM. Cardiopulmonary effects of the peripheral α2-adrenoseptor antagonist MK-467 in medetomidine sedated sheep receiving atipamezole. Association of Veterinary Anaesthetists Spring Meeting, Manchester, UK, 27.-28.4.2017.

  • Adam M, Keskitalo TK, Raekallio MR, Vainio OM. Cardiovascular and sedative effects of MK-467, a peripheral alpha2-adrenoceptor antagonist, in sheep sedated with intramuscular medetomidine. Association of Veterinary Anaesthetists Spring Meeting, Manchester, UK, 27.-28.4.2017.

  • Kallio-Kujala I, Raekallio M, Honkavaara J, Bennett RC, Turunen H, Vainio O. MK-467 accelerates the absorption of sedative agents in dogs – preliminary results. Association of Veterinary Anaesthetists Spring Meeting, Manchester, UK, 27.-28.4.2017. (poster)

  • Adam M, Salla K, Raekallio M, Honkavaara J, Mölsä S, Vainio O. Cardiopulmonary effects of MK-467, a peripheral alpha2-adrenoceptor antagonist, in sheep receiving medetomidine-ketamine. Association of Veterinary Anaesthetists Autumn Meeting, Prague, Czech Republic, 14-17.9.2016.

  • Pakkanen S, de Vries A, Raekallio M, Palviainen M, Vainio O. The effect of romifidine, MK-467, a peripheral alpha-2-adrenoceptor antagonist, and their combination on plasma glucose concentration in horses. Association of Veterinary Anaesthetists Autumn Meeting, Prague, Czech Republic, 14-17.9.2016.

  • Kaartinen MJ, Pelligand L, Restitutti F, Raekallio MR, Scheinin M, Vainio OM. 2016. Pharmacokinetic interaction of three doses of the peripheral alpha-2 antagonist MK-467 on the disposition of intramuscular medetomidine in dogs. Association of Veterinary Anaesthetists Spring Meeting, Lyon, France, 20-22.4.2016.

  • Salla K,  Tuns C, Junnila J, Raekallio M, Vainio O. 2016. Cardiovascular effects of the alpha-2-adrenoceptor antagonist MK-467 compared to glycopyrrolate during isoflurane anaesthesia in dogs premedicated with medetomidine. Association of Veterinary Anaesthetists Spring Meeting, Lyon, France, 20-22.4.2016.

  • Koskinen H, Raekallio M, Rajamäki M, Tapio H, Mykkänen A. 2015. Effects of general anaesthesia in dorsal recumbency to bronchoalveolar lavage cytology of healthy horses. Veterinary Comparative Respiratory Society, Edinburgh, UK, 8-10.10.2015

  • Hector RC, Rezende M, Mama K, Steffey EP, Bunnag N, Honkavaara J, Raekallio M, Vainio O. 2015. The effects of dexmedetomidine and MK-467 on the minimum alveolar concentration of sevoflurane in dogs. American College of Veterinary Anesthesia and Analgesia Annual Meeting. Washington DC, USA, 19.9.2015.

  • Restitutti F, Raekallio M, Kaartinen J, Honkavaara J, Wejberg O, Mikkola E, Scheinin M, Vainio O. 2015. Influence of MK-467 on the absorption of medetomidine after intramuscular administration in dogs – Preliminary results. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015.

  • Mama K, Rezende M, Steffey EP, Hector RC, Bunnag N, Honkavaara J, Raekallio M, Vainio O. 2015. Effect of two doses of the peripheral alpha-2-adrenoceptor antagonist MK-467 on the minimum alveolar concentration (MAC) of sevoflurane in dogs receiving dexmedetomidine. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015.

  • Restitutti F, Kaartinen J, Raekallio M, Wejberg O, Mikkola E, Honkavaara J, Vainio O. 2015. Cardiovascular and sedative effects of intramuscular co-administration of medetomidine and MK-467, a peripheral alpha-2-adrenoceptor antagonist, in dogs – Preliminary results. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015.

  • Turunen H, Raekallio M, Adam M, Helin H, Nevanperä K, Kallio-Kujala I, Honkavaara J, Restitutti F, Larenza P, Vainio O. 2015. The effects of MK-467, a peripheral α₂-adrenergic receptor antagonist, on the cardiovascular system and sedation in dogs receiving atipamezole to reverse medetomidine-induced sedation. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015.

  • Restitutti F, Honkavaara J, Menzies RA, Rosati T, Vainio O, Raekallio M, Larenza Menzies MP. 2015. Influence of acepromazine and/or a constant rate infusion of MK-467 on cardiovascular parameters of dogs anaesthetized with isoflurane and a step up infusion of dexmedetomidine – Preliminary data. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015.

  • Mama K, Rezende M, Steffey EP, Hector RC, Bunnag N, Honkavaara J, Raekallio M, Vainio O. 2015. Cardiovascular effects of dexmedetomidine alone and in combination with two doses of the peripheral α-2-adrenoceptor antagonist MK-467 in sevoflurane anesthetized dogs. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015.

  • Huuskonen V, Restitutti F, Honkavaara J, Raekallio M, Bennett R, Hagman M, Vainio O. 2015. The cardiovascular effects of dobutamine in isoflurane-anaesthetised dogs treated with dexmedetomidine and MK-467, a peripheral α2-antagonist. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015.

  • Kallio-Kujala I, Bennett RC, Raekallio M, Yatkin E, Scheinin M, Spillmann T, Vainio O. 2015. The effects of dexmedetomidine, a peripherally acting α2-antagonist (MK-467) and glibenclamide on blood glucose and lactate concentrations in dogs – Preliminary results. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 1-4.9.2015. 190. (Poster)

Salla K. 2017. Haemodynamic effects of MK-467 in combination with medetomidine and selected sedative and anaesthetic agents in dogs. ISBN:978-951-51-3860-6

Bennett R. 2017. The Impact of MK-467 on certain Pharmacokinetic and Pharmacodynamic Properties of Selected Drugs affecting the Central Nervous System in Dogs. ISBN:978-951-51-3509-4

Kaartinen J. 2016. The haemodynamic and pharmacologic interaction of medetomidine and peripheral antagonist MK-467 and their dose-dependency in dogs. ISBN:978-951-51-2460-9

Restitutti F. 2015. Central, cardiovascular and metabolic effects of dexmedetomidine associated with the selective peripheral alpha2-adrenoceptor antagonist MK-467 in dogs. ISBN:978-951-51-1735-9

Vainionpää M. 2014. Thermographic imaging in cats and dogs: usability as a clinical method. University of Helsinki. ISBN:978-952-10-9942-7

Hemmann K. 2014. Crib-biting in Horses: A Physiological and Genetic Study of Candidate Causative Factors. University of Helsinki. ISBN:978-952-9991-5

Palviainen M. 2014. Potential urinary biomarkers of acute kidney injury in domestic animals. University of Helsinki. ISBN:978-952-10-9797-3

Honkavaara J. 2012. Dexmedetomidine and MK-467, a peripherally acting α2-adrenoceptor antagonist, in dogs. University of Helsinki. ISBN:978-952-10-7744-9

Mustonen K. 2012. Pharmacology of ketoprofen administered orally to pigs: an experimental and clinical study. ISBN:978-952-10-8378-5

Thomson K. 2010. Species-specific and Indication-based Use of Antimicrobials in Dogs, Cats, Cattle and Horses in Finland : Data collected using three different methods. ISBN:978-952-10-6714-3

Väisänen M. 2006. Perioperative stress in dogs – different aspects of manifestation and characteristics with medetomidine and acepromazine preanaesthetic medication. ISBN:952-10-2975-7

Kuusela E. 2004. Dexmedetomidine and levomedetomidine, the isomers of medetomidine, in dogs. ISBN:952-10-1675-2

Osei A. 2004. Use of the alpha-2-adrenoceptor agonists, medetomidine and dexmedetomidine in the sedation and analgesia of domestic cats. ISBN:952-10-1908-5

Cognition and behavior related

Myller, A. (in preparation) Canine vision. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. Supervisor H. Törnqvist, supervising professor O. Vainio.

Inkinen L. (in preparation). Activity trackers in evaluating the connection of dog mobility and cognitive behaviour. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. Supervisor PhD M. Kujala, supervising professor O.Vainio

Koskela A. 2016. The evolutionary background of mammalian emotions and the measurement of them. Masters thesis in biology, Faculty of Biolocigal and Enviromental Sciences, University of Helsinki. Supervisors MSc S.Somppi and MSc H.Telkänranta, supervising professor H.Pietiäinen

Tammela T. 2014. Brain basis of canine sensory processing. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. Supervisor PhD M. Kujala, supervising professor O.Vainio (in Finnish)

Kukkola L. 2013. Environmental effects on social cognition of domestic dogs. Masters thesis in psychology, Faculty of Social Sciences, University of Göteborg. Supervisor MSc H. Törnqvist, supervising professor S. Hansen

Malkamäki S. 2012. The behavioral charasteristics of Finnish rottweiler dogs. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. Supervisors MCs S.Somppi, supervising professor A.Valros (in Finnish)

Valkonen M. 2012. The heritability of aggressiveness and fearfullness of Finnish rottweiler dogs. Masters thesis in animal science, Faculty of Agriculture and Forestry, University of Helsinki. Supervisors MSc S.Somppi, supervising professor J. Juga (in Finnish)

Haukka T. 2012. Dog emotions and personality of dogs from the owners point of view. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. Supervisors MSc S.Somppi, supervising professor A.Valros

Törnqvist H. 2011. The application of eye tracker in dog cognition studies. Masters Thesis in cognition, Faculty of Behavioural Sciences, University of Helsinki. Supervisors MSc S.Somppi, supervising professor C.M. Krause

 

Pain and pharmacology related (excerpts since 2015)

Hepolehto E. 2016. The use of immunosuppressive drugs in dogs and cats - a literature review. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. Supervisor Marja Raekallio, supervising professor Outi Vainio. (in Finnish)

Virtanen M. 2015. Alpha-2-agonists side effects in cats. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. (in Finnish)

Mikkola E. 2015. The effects of a combination of medetomidine and MK-467 on cardiovascular parameters in dogs. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. (in Finnish)

Wejberg O. 2015. The effects of the medetomidine and MK-467 on sedation and respiratory parameters. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. (in Finnish)

Huttunen A. 2015. Chronic pain physiology and drug therapy in dogs and cats. Licenciate thesis, Faculty of Veterinary Medicine, University of Helsinki. Supervisor Marja Raekallio, supervising professor Outi Vainio. (in Finnish)