Institute of Biotechnology (BI) is a part of Helsinki Institute of Life Science HiLIFE, with a mission to increase knowledge in biotechnology and integrative biology and use this for the benefit of society. BI aims to strengthen its position as an international outstanding research institute in biosciences profiled through high impact research and renowned scientists and to develop as an international, competitive and rewarding workplace sought after as a collaboration partner within the university and internationally.

BI was established in 1989 and is located on the Viikki Life Sciences Campus. The staff of ca. 300 is very international representing over 30 countries and consisting of researchers at all career stages, as well as technicians and supporting staff. BI is a founding member of Biocenter Finland, a national alliance coordinating biosciences through shared technologies, education and services. BI collaborates extensively with university faculties and other research units on campus in research and education of Masters and graduate students, and taking science to the society.

University of Helsinki, Institute of Biotechnology invites applications for a position of a

POST-DOCTORAL RESEARCHER
for a fixed-term of 3 years, starting September 1st 2017.

We are looking for an applicant with a PhD degree in the field of biology, biochemistry, pharmacy or equivalent, and a keen interest in the research field of neurodegenerative diseases, mainly for Amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. The successful candidate is expected to have an excellent track record, a strong background in neurosciences, a broad working knowledge of mouse genetics, stereotactic surgeries in rodents, molecular and cellular biology, microscope techniques and behavioral assays. Excellent written and verbal communication skills in English are required. The candidate is expected to work independently, and as part of a multidisciplinary research team, design experiments and perform research. Previous experience in cell culture, iPS cells, cell biology and protein biochemistry techniques and mouse models of degenerative diseases is considered a benefit.
The position is placed in an Academy of Finland-funded project, which aims at developing new treatments for ALS. The work includes experimentation with cell culture and transgenic mouse models using various cell biology, viral mediated gene expression, protein biochemistry and in vivo techniques.

The main research interests of our laboratory focus on novel trophic factors and their therapeutic effects in neurodegenerative diseases such as in ALS and in Parkinson’s disease. We have earlier shown that a novel trophic factor called CDNF (Cerebral Dopamine Neurotrophic Factor) is neuroprotective and neurorestorative in animal models of PD. CDNF is currently in phase 1/2 clinical trials on PD patients. The goal of the CDNF ALS project is to characterize the effects of CDNF and its novel variant in animal and in different cell culture models of ALS (such as in motoneurons derived from iPSCs from ALS patients) and take the molecules toward clinical trials.

The application should include a motivation letter (max 1 page) and a complete CV with:
- Education/previous degrees obtained,
- Prior work/research experience including research methods and list of publications,
- Recommendation letters or names and contact information of two references

The above attachments must be submitted as a single pdf file.

The salary (level 5) is based on the salary system of the Finnish Universities for teaching and research staff. In addition, the appointee will be paid a salary component based on personal work performance.

A trial period of 4 months will be applied.

Please, submit your application with the attachment file by August 15th 2017 using the University of Helsinki Recruitment System by clicking on the Apply link below. Internal applicants (i.e. current employees of the University of Helsinki) must submit their applications through the SAP HR portal.

Please fill in only the mandatory fields (*) in the Recruitment System, and deliver the attachment file as a single pdf file. More information about the work carried out by the team can be found at:
http://www.biocenter.helsinki.fi/bi/saarma/people/voutilainen.html

Enquiries about the position should be addressed to Senior Researcher Merja H Voutilainen: merja.h.voutilainen(at)helsinki.fi.

Apply at latest 15.08.2017

Due date

Tuesday, August 15, 2017