In Vivo Brain Microscopy Unit

IVBMU provide services in two-photon in vivo imaging of the brain and spinal cord in anesthetized and awake freely moving rodents.

Contact person: Leonard Khiroug, +358 45 635 2270, leonard.khirug@helsinki.fi

Location: Biomedicum, Haartmaninkatu 8, Meilahti Campus and Cultivator II, Viikinkaari 4, Viikki Campus

Services:

  • In vivo two-photon imaging of brain and spinal cord  in anesthetized and awake freely moving rodents

Instruments:

  • Olympus FV1000MP two-photon imaging system. SpectraPhysics MaiTai laser.
  • Femtonics Femto2D-Dual two-photon imaging system combining slower galvo and faster resonant scanner. SpectraPhysics MaiTai laser.
  • Hood for animal surgeries
  • Image analysis system with dedicated software

Applications:

  • Morphological studies of the brain and spinal cord on cellular and subcellular level in physiological conditions and disease models
  • Fast functional calcium imaging of brain neuronal networks
  • Brain pharmacokinetics and pharmacodynamics of fluorescently-labeled drugs

User fees:

The research infrastructure is supported by Neuroscience Center, University of Helsinki. The academic prices (excl. VAT) are listed below. Please, ask a quotation for your project.

Service

€/h

€/day

Scanner 1

61.5

 

Operator

 

 

Veterinary nurse

 

 

Use of image analysis software

 

 

Image analysis