Selected Publications of Our Users

Here is a list of publications from our users.

The papers in this list present the EM-work carried out with the help of our technical and/or academic staff.

If your paper is missing please inform us by sending email to Eija Jokitalo.
2024
  • Aimo-Koivisto E, Punakallio L, Järvinen R, Junnila J, Grönthal T, Rantala M., A pilot study of antimicrobial effects and ototoxicity of a Norway spruce (Picea abies) resin-based canine otic rinse product. Vet Dermatol. 2024 Jan 2. doi: 10.1111/vde.13229. 
2023
  • Ayazbayeva A, Baddam V, Shakhvorostov A, Gussenov I, Aseyev V, Yermaganbetov M, Kudaibergenov S. Amphoteric nano- and microgels with acrylamide backbone for potential application in oil recovery. Polymers Adv Tech, https://doi.org/10.1002/pat.6182
  • Barreiro K, Lay AC, Leparc G, Tran VDT, Rosler M, Dayalan L, Burdet F, Ibberson M, Coward RJM, Huber TB, Krämer BK, Delic D, Holthofer H. An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles J Extracell Vesicles. 2023 Feb;12(2):e12304. doi: 10.1002/jev2.12304.
  • Dwivedi OP, Barreiro K, Käräjämäki A, Valo E, Giri AK, Prasad RB, Roy RD, Thorn LM, Rannikko A, Holthöfer H, Gooding KM, Sourbron S, Delic D, Gomez MF; iBEAt; Groop PH, Tuomi T, Forsblom C, Groop L, Puhka M. Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease iScience. 2023 Apr 18;26(5):106686. doi: 10.1016/j.isci.2023.106686.
  • Grami E, Badawy S, Kiljunen S, Saidi N, Skurnik M. Characterization and genome analysis of Escherichia phage fBC-Eco01, isolated from wastewater in Tunisia Arch Virol. 2023 Jan 7;168(2):44. doi: 10.1007/s00705-022-05680-8
  • Gorski K, Jackson CB, Nyman TA, Rezov V, Battersby BJ, Lehesjoki AE. Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice. Front Mol Neurosci. 2023 May 12;16:1175851. doi: 10.3389/fnmol.2023.1175851
  • Huang Y, Gui J, Myllymäki SM, Mikkola ML, Shimmi O. Coordination of tissue homeostasis and growth by the Scribble-α-Catenin-Septate junction complex. iScience. 2023 Mar 22;26(4):106490. doi: 10.1016/j.isci.2023.106490.
  • Ignatenko O, Malinen S, Rybas S, Vihinen H, Nikkanen J, Kononov A, Jokitalo ES, Ince-Dunn G, Suomalainen A. Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes. J Cell Biol. 2023 Jan 2;222(1):e202203019. doi: 10.1083/jcb.202203019.
  • Joo S, Dhaygude K, Westerberg S, Krebs R, Puhka M, Holmström E, Syrjälä S, Nykänen AI, Lemström K. Transcriptomic Landscape of Circulating Extracellular Vesicles in Heart Transplant Ischemia-Reperfusion. Genes (Basel). 2023 Nov 18;14(11):2101. doi: 10.3390/genes14112101
  • Kalmbach L, Bourdon M, Belevich I, Safran J, Lemaire A, Heo JO, Otero S, Blob B, Pelloux J, Jokitalo E, Helariutta Y. Putative pectate lyase PLL12 and callose deposition through polar CALS7 are necessary for long-distance phloem transport in Arabidopsis. Curr Biol. 2023 Mar 13;33(5):926-939.e9. doi: 10.1016/j.cub.2023.01.038.
  • Kangas P, Nyman TA, Metsähonkala L, Burns C, Tempest R, Williams T, Karttunen J, Jokinen TS. Towards optimised extracellular vesicle proteomics from cerebrospinal fluid. Sci Rep. 2023 Jun 12;13(1):9564. doi: 10.1038/s41598-023-36706-z.
  • Kankuri E, Finckenberg P, Leinonen J, Tarkia M, Björk S, Purhonen J, Kallijärvi J, Kankainen M, Soliymani R, Lalowski M, Mervaala E. Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity. Exp Mol Med. 2023 Apr 3. doi: 10.1038/s12276-023-00967-5
  • Karvinen S, Korhonen TM, Sievänen T, Karppinen JE, Juppi HK, Jakoaho V, Kujala UM, Laukkanen JA, Lehti M, Laakkonen EK. Extracellular vesicles and high-density lipoproteins: Exercise and oestrogen-responsive small RNA carriers. J Extracell Vesicles. 2023 Feb;12(2):e12308. doi: 10.1002/jev2.12308.
  • Konovalova S, Torregrosa-Muñumer R, Manjunath P, Liu X, Baral S, Fatima K, Holopainen M, Kvist J, Rajendran J, Yang Y, Varjosalo M, Käkelä R, Somerharju P, Tyynismaa H. Small mitochondrial protein NERCLIN regulates cardiolipin homeostasis and mitochondrial ultrastructure. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2210599120. doi: 10.1073/pnas.2210599120. 
  • Lambidis E, Chen CC, Lumen D, Sánchez AIF, Sarparanta M, Cheng RH, Airaksinen AJ. Biological evaluation of integrin α3β1-targeted 68Ga-labeled HEVNPs in HCT 116 colorectal tumor-bearing mice. Eur J Pharm Sci. 2023 Jan 1;180:106336. doi: 10.1016/j.ejps.2022.106336
  • Lampi M, Gregorova P, Qasim MS, Ahlblad NCV, Sarin LP, Bacteriophage infection of the marine bacterium Shewanella glacialimarina induces dynamic changes in tRNA modifications. Microorganisms 2023, 11, 355. doi.org/10.3390/microorganisms11020355
  • Lapatto HAK, Kuusela M, Heikkinen A, Muniandy M, van der Kolk BW, Gopalakrishnan S, Pöllänen N, Sandvik M, Schmidt MS, Heinonen S, Saari S, Kuula J, Hakkarainen A, Tampio J, Saarinen T, Taskinen MR, Lundbom N, Groop PH, Tiirola M, Katajisto P, Lehtonen M, Brenner C, Kaprio J, Pekkala S, Ollikainen M, Pietiläinen KH, Pirinen E. Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Sci Adv. 2023 Jan 13;9(2):eadd5163. doi: 10.1126/sciadv.add5163
  • Lembinen S, Cieslak M, Zhang T, Mackenzie K, Elomaa P, Prusinkiewicz P, Hytönen T. Diversity of woodland strawberry inflorescences arises from heterochrony regulated by TERMINAL FLOWER 1 and FLOWERING LOCUS T. Plant Cell. 2023 Mar 21:koad086. doi: 10.1093/plcell/koad086
  • Maaninka K, Neuvonen M, Kerkelä E, Hyvärinen K, Palviainen M, Kamali-Moghaddam M, Federico A, Greco D, Laitinen S, Öörni K, Siljander PR. OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression.Eur J Cell Biol. 2023 Mar 15;102(2):151311. doi: 10.1016/j.ejcb.2023.151311
  • Mohammadi K, Saris PEJ. Antibiofilm Effect of Curcumin on Saccharomyces boulardii during Beer Fermentation and Bottle Aging Biomolecules. 2023 Sep 8;13(9):1367. doi: 10.3390/biom13091367.
  • Molinaro G, Fontana F, Pareja Tello R, Wang S, López Cérda S, Torrieri G, Correia A, Waris E, Hirvonen JT, Barreto G, A Santos H. In Vitro Study of the Anti-inflammatory and Antifibrotic Activity of Tannic Acid-Coated Curcumin-Loaded Nanoparticles in Human Tenocytes. ACS Appl Mater Interfaces. 2023 May 17;15(19):23012-23023. doi: 10.1021/acsami.3c05322
  • Paukštytė J, López Cabezas RM, Feng Y, Tong K, Schnyder D, Elomaa E, Gregorova P, Doudin M, Särkkä M, Sarameri J, Lippi A, Vihinen H, Juutila J, Nieminen A, Törönen P, Holm L, Jokitalo E, Krisko A, Huiskonen J, Sarin LP, Hietakangas V, Picotti P, Barral Y, Saarikangas J. Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity. Mol Cell. 2023 Sep 21;83(18):3360-3376.e11. doi: 10.1016/j.molcel.2023.08.015. 
  • Saari H, Pusa R, Marttila H, Yliperttula M, Laitinen S. Development of tandem cation exchange chromatography for high purity extracellular vesicle isolation: The effect of ligand steric availability. J Chromatogr A. 2023 Sep 27;1707:464293. doi: 10.1016/j.chroma.2023.464293. 
  • Scurti E, Martins JP, Celia C, Palumbo P, Lombardi F, Iannotta D, Di Marzio L, Santos HA, Viitala T. In Vitro Characterization and Real-Time Label-Free Assessment of the Interaction of Chitosan-Coated Niosomes with Intestinal Cellular MonolayersLangmuir. 2023 Jun 13;39(23):8255-8266. doi: 10.1021/acs.langmuir.3c00728.  
  • Senju Y, Mushtaq T, Vihinen H, Manninen A, Saarikangas J, Ven K, Engel U, Varjosalo M, Jokitalo E, Lappalainen P. Actin-rich lamellipodia-like protrusions contribute to the integrity of epithelial cell-cell junctions. J Biol Chem. 2023 May;299(5):104571. doi: 10.1016/j.jbc.2023.104571.
  • Sporbeck K, Haas ML, Pastor-Maldonado CJ, Schüssele DS, Hunter C, Takacs Z, Diogo de Oliveira AL, Franz-Wachtel M, Charsou C, Pfisterer SG, Gubas A, Haller PK, Knorr RL, Kaulich M, Macek B, Eskelinen EL, Simonsen A, Proikas-Cezanne T. The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension. Commun Biol. 2023 Aug 24;6(1):872. doi: 10.1038/s42003-023-05236-9
  • Taavitsainen-Wahlroos E, Reigada I, Sulmona I, Hanski L. Impact of azithromycin, doxycycline and redox-active small molecules on amoxicillin-induced Chlamydia pneumoniae persistence. Biomed Pharmacother. 2023 Nov;167:115451. doi: 10.1016/j.biopha.2023.115451.
  • Tapeinos C, Torrieri G, Wang S, Martins JP, Santos HA. Evaluation of cell membrane-derived nanoparticles as therapeutic carriers for pancreatic ductal adenocarcinoma using an in vitro tumour stroma model. J Control Release. 2023 Oct;362:225-242. doi: 10.1016/j.jconrel.2023.08.045.
  • Tramontano C, Martins JP, De Stefano L, Kemell M, Correia A, Terracciano M, Borbone N, Rea I, Santos HA. Microfluidic-assisted production of gastro-resistant active-targeted diatomite nanoparticles for the local release of galunisertib in metastatic colorectal cancer cells. Adv Healthc Mater. 2023 Jan;12(6):e2202672. doi: 10.1002/adhm.202202672
  • Wang L, Hilander T, Liu X, Tsang HY, Eriksson O, Jackson CB, Varjosalo M, Zhao H. GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation Cell Mol Life Sci. 2023 Nov 16;80(12):361. doi: 10.1007/s00018-023-05014-0.
  • Waszczak C, Yarmolinsky D, Leal Gavarrón M, Vahisalu T, Sierla M, Zamora O, Carter R, Puukko T, Sipari N, Lamminmäki A, Durner J, Ernst D, Winkler JB, Paulin L, Auvinen P, Fleming AJ, Andersson MX, Kollist H, Kangasjärvi J. Synthesis and import of GDP-l-fucose into the Golgi affect plant-water relations. New Phytol. 2023 Nov 14. doi: 10.1111/nph.19378
2022
  • Baddam V, Välinen L, Kuckling L, Tenhu H., Morphological transitions of cationic PISA particles by salt, triflate ions and temperature; comparison of three polycations. 2022 Polym. Chem., 2022, 13, 3790-3799. doi: 10.1039/D2PY00301E
  • Bäck N, Mains RE, Eipper BA. PAM: diverse roles in neuroendocrine cells, cardiomyocytes, and green algae. FEBS J, 289: 4470-4496. doi.org/10.1111/febs.16049 
  • Cheng R, Jiang L, Gao H, Liu Z, Mäkilä E, Wang S, Saiding Q, Xiang L, Tang X, Shi M, Liu J, Pang L, Salonen J, Hirvonen J, Zhang H, Cui W, Shen B, Santos HA. A pH-Responsive Cluster Metal-Organic Framework Nanoparticle for Enhanced Tumor Accumulation and Antitumor Effect. Adv Mater. 2022 Oct;34(42):e2203915. doi: 10.1002/adma.202203915
  • Demina TA, Luhtanen AM, Roux S, Oksanen HM. Virus-Host Interactions and Genetic Diversity of Antarctic Sea Ice Bacteriophages. mBio. 2022 Jun 28;13(3):e0065122. doi: 10.1128/mbio.00651-22. 
  • Englund, M, 2022: 128 years from discovery to description: integrative taxonomy of a forgotten moth from Southern Africa (Lepidoptera: Geometridae). MSc thesis, Faculty of Biological and Environmental Sciences, University of Helsinki.
  • Englund JI, Bui H, Dinç DD, Paavolainen O, McKenna T, Laitinen S, Munne P, Klefström J, Peuhu E, Katajisto P. Laminin matrix adhesion regulates basal mammary epithelial cell identity. J Cell Sci. 2022 Dec 1;135(23):jcs260232. doi: 10.1242/jcs.260232
  • Giorgi L, Niemelä A, Kumpula EP, Natri O, Parkkila P, Huiskonen JT, Koivuniemi A. Mechanistic Insights into the Activation of Lecithin-Cholesterol Acyltransferase in Therapeutic Nanodiscs Composed of Apolipoprotein A-I Mimetic Peptides and Phospholipids. Mol Pharm. 2022 Sep 16. doi: 10.1021/acs.molpharmaceut.2c00540
  • Gomes AS, Correia A, Rahikkala A, Mäkilä E, Pinto MM, Sousa E, Salonen J, Saraiva L, Santos HA. Folic acid-mesoporous silicon nanoparticles enhance the anticancer activity of the p73-activating small molecule LEM2. Int J Pharm. 2022 Aug 25;624:121959. doi: 10.1016/j.ijpharm.2022.121959
  • Herbers E, Patrikoski M, Wagner A, Jokinen R, Hassinen A, Heinonen S, Miettinen S, Peltoniemi H, Pirinen E, Pietiläinen KH. Preventing White Adipocyte Browning during Differentiation In Vitro: The Effect of Differentiation Protocols on Metabolic and Mitochondrial Phenotypes.Stem Cells Int. 2022 Apr 5;2022:3308194. doi: 10.1155/2022/3308194. 
  • Hokkala E, Strachan CJ, Agopov M, Semjonov K, Heinämäki J, Yliruusi J, Svanbäck S. Fast imaging-based single particle analysis method for solubility determination. Int J Pharm. 2022 Aug 25;624:121976. doi: 10.1016/j.ijpharm.2022.121976
  • Höglund N, Koho N, Rossi H, Karttunen J, Mustonen AM, Nieminen P, Rilla K, Oikari S, Mykkänen A. Isolation of Extracellular Vesicles From the Bronchoalveolar Lavage Fluid of Healthy and Asthmatic Horses. Front Vet Sci. 2022 Jun 21;9:894189. doi: 10.3389/fvets.2022.894189
  • Ikkala K, Raatikainen S, Koivula H, Michon F. Zebrafish cornea formation and homeostasis reveal a slow maturation process, similarly to terrestrial vertebrates' corneas. Front Physiol. 2022 Nov 1;13:906155. doi: 10.3389/fphys.2022.906155
  • Ikkala K, Raatikainen S, Michon F. Zebrafish Corneal Wound Healing: From Abrasion to Wound Closure Imaging Analysis. J Vis Exp. 2022 Mar 1;(181). doi: 10.3791/63605
  • Ikkala K, Stratoulias V, Michon F. Unilateral zebrafish corneal injury induces bilateral cell plasticity supporting wound closure, Sci Rep. 2022 Jan 7;12(1):161. doi: 10.1038/s41598-021-04086-x
  • Kuribayashi T, Lankinen P, Hietala S, Mikkonen KS. Dense and continuous networks of aerial hyphae improve flexibility and shape retention of mycelium composite in the wet state. Composites Part A: Applied Science and Manufacturing, 2022, 152, 106688. doi: 10.1016/j.compositesa.2021.106688
  • Kyykallio H, Faria AVS, Hartmann R, Capra J, Rilla K, Siljander PR. A quick pipeline for the isolation of 3D cell culture-derived extracellular vesicles.J Extracell Vesicles. 2022 Oct;11(10):e12273. doi: 10.1002/jev2.12273
  • Lafuente-Gómez N, Wang S, Fontana F, Dhanjani M, García-Soriano D, Correia A, Castellanos M, Rodriguez Diaz C, Salas G, Santos HA, Somoza Á. Synergistic immunomodulatory effect in macrophages mediated by magnetic nanoparticles modified with miRNAs. Nanoscale. 2022 Aug 11;14(31):11129-11138. doi: 10.1039/d2nr01767a
  • Li J, Huang D, Cheng R, Figueiredo P, Fontana F, Correia A, Wang S, Liu Z, Kemell M, Torrieri G, Mäkilä EM, Salonen JJ, Hirvonen J, Gao Y, Li J, Luo Z, Santos HA, Xia B. Multifunctional Biomimetic Nanovaccines Based on Photothermal and Weak-Immunostimulatory Nanoparticulate Cores for the Immunotherapy of Solid Tumors. Adv Mater. 2022 Mar;34(9):e2108012. doi: 10.1002/adma.202108012
  • Martins JP, Figueiredo P, Wang S, Espo E, Celi E, Martins B, Kemell M, Moslova K, Mäkilä E, Salonen J, Kostiainen MA, Celia C, Cerullo V, Viitala T, Sarmento B, Hirvonen J, Santos HA. Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium. Bioact Mater. 2021 Aug 10;9:299-315. doi: 10.1016/j.bioactmat.2021.08.007.
  • Saraswat M, Przybyla B, Joenvaara S, Tohmola T, Strandin T, Puhka M, Jouppila A, Lassila R, Renkonen R. Urinary extracellular vesicles carry multiple activators and regulators of coagulation. Front Cell Dev Biol. 2022 Sep 7;10:967482. doi: 10.3389/fcell.2022.967482
  • Merivaara A, Kekkonen J, Monola J, Koivunotko E, Savolainen M, Silvast T, Svedström K, Diaz A, Holler M, Korhonen O, Yliperttula M, Valkonen S. Near-infrared analysis of nanofibrillated cellulose aerogel manufacturing. Int J Pharm. 2022 Apr 5;617:121581. doi: 10.1016/j.ijpharm.2022.121581.
  • Morais M, Machado V, Dias F, Figueiredo P, Palmeira C, Martins G, Fernandes R, Malheiro AR, Mikkonen KS, Teixeira AL, Medeiros R. Glucose-Functionalized Silver Nanoparticles as a Potential New Therapy Agent Targeting Hormone-Resistant Prostate Cancer cells. Int J Nanomedicine. 2022 Sep 16;17:4321-4337. doi: 10.2147/IJN.S364862
  • Neupane N, Rajendran J, Kvist J, Harjuhaahto S, Hu B, Kinnunen V, Yang Y, Nieminen AI, Tyynismaa H. Inter-organellar and systemic responses to impaired mitochondrial matrix protein import in skeletal muscle. Commun Biol. 2022 Oct 5;5(1):1060. doi: 10.1038/s42003-022-04034-z.
  • Puhka M, Thierens L, Nicorici D, Forsman T, Mirtti T, Af Hällström T, Serkkola E, Rannikko A. 
    Exploration of Extracellular Vesicle miRNAs, Targeted mRNAs and Pathways in Prostate Cancer: Relation to Disease Status and Progression.Cancers (Basel). 2022 Jan 21;14(3):532. doi: 10.3390/cancers14030532
  • Portinha IM, Douillard FP, Korkeala H, Lindström M. Sporulation Strategies and Potential Role of the Exosporium in Survival and Persistence of Clostridium botulinum. Int J Mol Sci. 2022 Jan 11;23(2):754. doi: 10.3390/ijms23020754
  • Prusinkiewicz P, Zhang T, Owens A, Cieslak M, Elomaa P. Phyllotaxis without symmetry: what can we learn from flower heads? J Exp Bot. 2022 Jun 2;73(11):3319-3329. doi: 10.1093/jxb/erac101
  • Saha S, Lõhmus A, Dutta P, Pollari M, Mäkinen K. Interplay of HCPro and CP in the Regulation of Potato Virus A RNA Expression and Encapsidation. Viruses. 2022 Jun 7;14(6):1233. doi: 10.3390/v14061233
  • Sainio MT, Rasila T, Molchanova SM, Järvilehto J, Torregrosa-Muñumer R, Harjuhaahto S, Pennonen J, Huber N, Herukka SK, Haapasalo A, Zetterberg H, Taira T, Palmio J, Ylikallio E, Tyynismaa H. Neurofilament light regulates axon caliber, synaptic activity, and organelle trafficking in cultured human motor neurons. Front Cell Dev Biol. 2022 Feb 14;9:820105. doi: 10.3389/fcell.2021.820105
  • Zhang Z, Douillard FP, Korkeala H, Lindström M. Specific Isolation of Clostridium botulinum Group I Cells by Phage Lysin Cell Wall Binding Domain with the Aid of S-Layer Disruption. Int J Mol Sci. 2022 Jul 29;23(15):8391. doi: 10.3390/ijms23158391
  • Zielke N, Vähärautio A, Liu J, Kivioja T, Taipale J. Upregulation of ribosome biogenesis via canonical E-boxes is required for Myc-driven proliferation. Dev Cell. 2022 Apr 25;57(8):1024-1036.e5. doi: 10.1016/j.devcel.2022.03.018.
  • Zini J, Saari H, Ciana P, Viitala T, Lõhmus A, Saarinen J, Yliperttula M. Infrared and Raman spectroscopy for purity assessment of extracellular vesicles. Eur J Pharm Sci. 2022 May 1;172:106135. doi: 10.1016/j.ejps.2022.106135
2021
  • Aho V, Salminen S, Mattola S, Gupta A, Flomm F, Sodeik B, Bosse JB, Vihinen-Ranta M. Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane. PLoS Pathog. 2021 Dec 15;17(12):e1010132. doi: 10.1371/journal.ppat.1010132
  • Baddam V, Välinen L, Tenhu H. Thermoresponsive Polycation-Stabilized Nanoparticles through PISA. Control of Particle Morphology with a Salt. Macromolecules 2021, 54, 9, 4288–4299, doi: 10.1021/acs.macromol.0c02771
  • Barreiro K, Dwivedi OP, Valkonen S, Groop PH, Tuomi T, Holthofer H, Rannikko A, Yliperttula M, Siljander P, Laitinen S, Serkkola E, Af Hällström T, Forsblom C, Groop L, Puhka M. Urinary extracellular vesicles: Assessment of pre-analytical variables and development of a quality control with focus on transcriptomic biomarker research. J Extracell Vesicles. 2021 Oct;10(12):e12158. doi: 10.1002/jev2.12158
  • Dichlberger A, Zhou K, Bäck N, Nyholm T, Backman A, Mattjus P, Ikonen E, Blom T. LAPTM4B controls the sphingolipid and ether lipid signature of small extracellular vesicles. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Feb;1866(2):158855. doi: 10.1016/j.bbalip.2020.158855

  • Eskelinen E-L, Kallio K. Ultrastructure of the Macroautophagy Pathway in Mammalian Cells. Imaging and Quantifying Neuronal Autophagy, 2021, 13-21, doi: 10.1007/978-1-0716-1589-8_2.

  • Feola S, Haapala M, Peltonen K, Capasso C, Martins B, Antignani G, Federico A, Pietiäinen V, Chiaro J, Feodoroff M, Russo S, Rannikko A, Fusciello M, Koskela S, Partanen J, Hamdan F, Tähkä SM, Ylösmäki E, Greco D, Grönholm M, Kekarainen T, Eshaghi M, Gurvich OL, Ylä-Herttuala S, M Branca RM, Lehtiö J, Sikanen TM, Cerullo V. PeptiCHIP: A Microfluidic Platform for Tumor Antigen Landscape Identification. ACS Nano. 2021 Oct 26;15(10):15992-16010. doi: 10.1021/acsnano.1c04371

  • Figueiredo P, Lahtinen MH, Agustin MB, de Carvalho DM, Hirvonen SP, Penttilä PA, Mikkonen KS. Green Fabrication Approaches of Lignin Nanoparticles from Different Technical Lignins: A Comparison Study. ChemSusChem. 2021 Nov 4;14(21):4718-4730. doi: 10.1002/cssc.202101356

  • Lindfors S, Polianskyte-Prause Z, Bouslama R, Lehtonen E, Mannerla M, Nisen H, Tienari J, Salmenkari H, Forsgård R, Mirtti T, Lehto M, Groop PH, Lehtonen S. Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo. Diabetologia. 2021 Aug;64(8):1866-1879. doi: 10.1007/s00125-021-05473-9.

  • Merivaara A, Zini J, Koivunotko E, Valkonen S, Korhonen O, Fernandes FM, Yliperttula M. Preservation of biomaterials and cells by freeze-drying: Change of paradigm. J Control Release. 2021 Aug 10;336:480-498. doi: 10.1016/j.jconrel.2021.06.042

  • Koivunotko E, Merivaara A, Niemelä A, Valkonen S, Manninen K, Mäkinen H, Viljanen M, Svedström K, Diaz A, Holler M, Zini J, Paasonen L, Korhonen O, Huotari S, Koivuniemi A, Yliperttula M. Molecular Insights on Successful Reconstitution of Freeze-Dried Nanofibrillated Cellulose Hydrogel.ACS Appl Bio Mater. 2021 Sep 20;4(9):7157-7167. doi: 10.1021/acsabm.1c00739

  • Martins JP, Figueiredo P, Wang S, Espo E, Celi E, Martins B, Kemell M, Moslova K, Mäkilä E, Salonen J, Kostiainen MA, Celia C, Cerullo V, Viitala T, Sarmento B, Hirvonen J, Santos HA. Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium.Bioact Mater. 2021 Aug 10;9:299-315. doi: 10.1016/j.bioactmat.2021.08.007

  • ​​​​​​​Sainio MT, Rasila T, Molchanova SM, Järvilehto J, Torregrosa-Muñumer R, Harjuhaahto S, Pennonen J, Huber N, Herukka SK, Haapasalo A, Zetterberg H, Taira T, Palmio J, Ylikallio E, Tyynismaa H. Neurofilament Light Regulates Axon Caliber, Synaptic Activity, and Organelle Trafficking in Cultured Human Motor Neurons. Front Cell Dev Biol. 2022 Feb 14;9:820105. doi: 10.3389/fcell.2021.820105

  • Sihvonen P, Murillo-Ramos L, Wahlberg N, Hausmann A, Zilli A, Ochse M, Staude HS. Insect taxonomy can be difficult: a noctuid moth (Agaristinae: Aletopus imperialis) and a geometrid moth (Sterrhinae: Cartaletis dargei) combined into a cryptic species complex in eastern Africa (Lepidoptera). PeerJ. 2021 Jun 25;9:e11613. doi: 10.7717/peerj.11613.

  • Zhang T, Wang F, Elomaa P. Repatterning of the inflorescence meristem in Gerbera hybrida after wounding. J Plant Res. 2021 Feb 4. doi: 10.1007/s10265-021-01253-z
2020

  • Barreiro K, Dwivedi OP, Leparc G, Rolser M, Delic D, Forsblom C, Groop PH, Groop L, Huber TB, Puhka M, Holthofer H. Comparison of urinary extracellular vesicle isolation methods for transcriptomic biomarker research in diabetic kidney disease. J Extracell Vesicles. 2020 Dec;10(2):e12038. doi: 10.1002/jev2.12038

  • Bäck N, Luxmi R, Powers KG, Mains RE, Eipper BA. Peptidylglycine α-amidating monooxygenase is required for atrial secretory granule formation. Proc Natl Acad Sci USA. 2020 Jul 28;117(30):17820-17831. doi: 10.1073/pnas.2004410117

  • De S, Pollari M, Varjosalo M, Mäkinen K. Association of host protein VARICOSE with HCPro within a multiprotein complex is crucial for RNA silencing suppression, translation, encapsidation and systemic spread of potato virus A infection. PLoS Pathog. 2020 Oct 12;16(10):e1008956. doi: 10.1371/journal.ppat.1008956

  • Jyske T, Kuroda K, Keriö S, Pranovich A, Linnakoski R, Hayashi N, Aoki D, Fukushima K., Localization of (+)-Catechin in Picea abies Phloem: Responses to Wounding and Fungal Inoculation. Molecules. 2020 Jun 26;25(12):2952. doi: 10.3390/molecules25122952.
  • Hiippala K, Barreto G, Burrello C, Diaz-Basabe A, Suutarinen M, Kainulainen V, Bowers JR, Lemmer D, Engelthaler DM, Eklund KK, Facciotti F, Satokari R. Novel Odoribacter splanchnicus Strain and Its Outer Membrane Vesicles Exert Immunoregulatory Effects in vitro. Front Microbiol. 2020 Nov 12;11:575455. doi: 10.3389/fmicb.2020.575455.
  • Mansikkala T, Patanen M, Kärkönen A, Korpinen R, Pranovich A, Ohigashi T, Swaraj S, Seitsonen J, Ruokolainen J, Huttula M, Saranpää P, Piispanen R. Lignans in Knotwood of Norway Spruce: Localisation with Soft X-ray Microscopy and Scanning Transmission Electron Microscopy with Energy Dispersive X-ray Spectroscopy. Molecules. 2020 Jun 30;25(13):E2997. doi: 10.3390/molecules25132997.
  • Piironen K, Haapala M, Talman V, Järvinen P, Sikanen T. Cell adhesion and proliferation on common 3D printing materials used in stereolithography of microfluidic devices. Lab Chip. 2020 Jun 30;20(13):2372-2382. doi: 10.1039/d0lc00114g
  • Pollari M, De S, Wang A, Mäkinen K. The potyviral silencing suppressor HCPro recruits and employs host ARGONAUTE1 in pro-viral functions. PLoS Pathog. 2020 Oct 8;16(10):e1008965. doi: 10.1371/journal.ppat.1008965
  • Saari H, Turunen T, Lõhmus A, Turunen M, Jalasvuori M, Butcher SJ, Ylä-Herttuala S, Viitala T, Cerullo V, Siljander PRM, Yliperttula M. Extracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery. J Extracell Vesicles. 2020 Apr 17;9(1):1747206. doi: 10.1080/20013078.2020.1747206. eCollection 2020.
  • Syrjä P, Palviainen M, Jokinen T, Kyöstilä K, Lohi H, Roosje P, Anderegg L, Leeb T, Sukura A, Eskelinen EL. Altered Basal Autophagy Affects Extracellular Vesicle Release in Cells of Lagotto Romagnolo Dogs With a Variant ATG4D. Vet Pathol. 2020 Nov;57(6):926-935. doi: 10.1177/0300985820959243.
2019
  • Aho V, Mäntylä E, Ekman A, Hakanen S, Mattola S, Chen J, Weinhardt V, Ruokolainen V, Sodeik B, Larabell C and Vihinen-Ranta M. "Quantitative Microscopy Reveals Stepwise Alteration of Chromatin Structure during Herpesvirus Infection", Viruses (2019) DOI:10.3390/v11100935
  • Akl MA, Kartal-Hodzic A, Suutari T, Oksanen T, Montagner IM, Rosato A, Ismael HR, Afouna MI, Caliceti P, Yliperttula M, Samy AM, Mastrotto F, Salmaso S and Viitala T. "Real-Time Label-Free Targeting Assessment and in Vitro Characterization of Curcumin-Loaded Poly-lactic-co-glycolic Acid Nanoparticles for Oral Colon Targeting", ACS Omega (2019) DOI:10.1021/acsomega.9b02086
  • Anwar T, Liu X, Suntio T, Marjamäki A, Biazik J, Chan EYW, Varjosalo M and Eskelinen E. "ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases", Cells (2019) DOI:10.3390/cells8050475
  • Auvinen K, Lokka E, Mokkala E, Jäppinen N, Tyystjärvi S, Saine H, Peurla M, Shetty S, Elima K, Rantakari P and Salmi M. "Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated.", Sci Rep (2019) DOI:10.1038/s41598-019-52068-x
  • Bauleth‐Ramos T, Shih T, Shahbazi M, Najibi AJ, Mao AS, Liu D, Granja P, Santos HA, Sarmento B and Mooney DJ. "Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination", Advanced Functional Materials (2019) DOI:10.1002/adfm.201903686
  • O'Connell Motherway M, Houston A, O’Callaghan G, Reunanen J, O’Brien F, O’Driscoll T, Casey PG, de Vos WM, van Sinderen D and Shanahan F. "A Bifidobacterial pilus‐associated protein promotes colonic epithelial proliferation", Molecular Microbiology (2019) DOI:10.1111/mmi.14155
  • Dufurrena Q, Bäck N, Mains RE, Hodgson L, Tanowitz H, Mandela P, Eipper E, Kuliawat R. Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion. J Mol Endocrinol. 2018 Nov 1. pii: JME-18-0048.R2. doi: 10.1530/JME-18-0048. 
  • Figueiredo P, Sipponen MH, Lintinen K, Correia A, Kiriazis A, Yli‐Kauhaluoma J, Österberg M, George A, Hirvonen J, Kostiainen MA and Santos HA. "Preparation and Characterization of Dentin Phosphophoryn-Derived Peptide-Functionalized Lignin Nanoparticles for Enhanced Cellular Uptake", Small (2019) DOI:10.1002/smll.201901427
  • Hassan G, Forsman N, Wan X, Keurulainen L, Bimbo LM, Johansson L, Sipari N, Yli-Kauhaluoma J, Zimmermann R, Stehl S, Werner C, Saris PEJ, Österberg M and Moreira VM. "Dehydroabietylamine-Based Cellulose Nanofibril Films: A New Class of Sustainable Biomaterials for Highly Efficient, Broad-Spectrum Antimicrobial Effects", ACS Sustainable Chemistry & Engineering (2019) DOI:10.1021/acssuschemeng.8b05658
  • Heinimäki S, Hankaniemi MM, Sioofy-Khojine AB, Laitinen OH, Hyöty H, Hytönen VP, Vesikari T and Blazevic V. "Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus.", Vaccine (2019) DOI:10.1016/j.vaccine.2019.09.072
  • Jackson CB, Huemer M, Bolognini R, Martin F, Szinnai G, Donner BC, Richter U, Battersby BJ, Nuoffer J, Suomalainen A and Schaller A. "A variant in MRPS14 (uS14m) causes perinatal hypertrophic cardiomyopathy with neonatal lactic acidosis, growth retardation, dysmorphic features and neurological involvement", Hum Mol Genet (2019) DOI:10.1093/hmg/ddy374
  • Johansson JK, Karema-Jokinen VI, Hakanen S, Jylhä A, Uusitalo H, Vihinen-Ranta M, Skottman H, Ihalainen TO and Nymark S. "Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium", BMC Biol. (2019) DOI:10.1186/s12915-019-0681-1
  • Kiiski IMA, Pihlaja T, Urvas L, Witos J, Wiedmer SK, Jokinen VP and Sikanen TM. "Enzyme Immobilization: Overcoming the Pitfalls of Cytochrome P450 Immobilization through the Use of Fusogenic Liposomes (Adv. Biosys. 1/2019)", Advanced Biosystems (2019) DOI:10.1002/adbi.201970012
  • Le Joncour V, Martins A, Puhka M, Isola J, Salmikangas M, Laakkonen P, Joensuu H and Barok M. "A Novel Anti-HER2 Antibody–Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine", Mol Cancer Ther (2019)
  • Mattinen M, Popov G, Vehkamäki M, King PJ, Mizohata K, Jalkanen P, Räisänen J, Leskelä M and Ritala M. "Atomic Layer Deposition of Emerging 2D Semiconductors, HfS2 and ZrS2, for Optoelectronics", Chem. Mater. (2019) DOI:10.1021/acs.chemmater.9b01688
  • Mannerström B, Kornilov R, Abu-Shahba AG, Chowdhury IM, Sinha S, Seppänen-Kaijansinkko R and Kaur S. "Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles", Epigenetics (2019) DOI:10.1080/15592294.2019.1585177
  • Mannerström B, Paananen RO, Abu-Shahba AG, Moilanen J, Seppänen-Kaijansinkko R and Kaur S. "Extracellular small non-coding RNA contaminants in fetal bovine serum and serum-free media", Scientific Reports (2019) DOI:10.1038/s41598-019-41772-3
  • Mäntymäki M, Atosuo E, Heikkilä MJ, Vehkamäki M, Mattinen M, Mizohata K, Räisänen J, Ritala M and Leskelä M. "Studies on solid state reactions of atomic layer deposited thin films of lithium carbonate with hafnia and zirconia" Journal of Vacuum Science & Technology A (2019) DOI:10.1116/1.5081494
  • Popov G, Mattinen M, Hatanpää T, Vehkamäki M, Kemell M, Mizohata K, Räisänen J, Ritala M and Leskelä M. "Atomic Layer Deposition of PbI2 Thin Films", Chemistry of Materials (2019) DOI:10.1021/acs.chemmater.8b04969
  • Pulli I, Löf C, Blom T, Asghar MY, Lassila T, Bäck N, Lin KL, Nyström JH, Kemppainen K, Toivola DM, Dufour E, Sanz A, Cooper HM, Parys JB, Törnquist K. Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells. Biochim Biophys Acta Mol Cell Res. 2019 Sep;1866(9):1475-1486. doi: 10.1016/j.bbamcr.2019.06.006. Epub 2019 Jun 17.
  • Seppälä S, Vehkamäki M, Mizohata K, Noh W, Räisänen J, Ritala M and Leskelä M. "Comparative study on the use of novel heteroleptic cyclopentadienyl-based zirconium precursors with H2O and O3 for atomic layer deposition of ZrO2", Journal of Vacuum Science & Technology A (2019) DOI:10.1116/1.5079539
2018
  • Atanasova NS, Demina TA, Krishnam Rajan Shanthi SV, Oksanen HM, and Bamford DH. 2018. Extremely halophilic pleomorphic archaeal virus HRPV9 extends the diversity of pleolipoviruses with integrases. Res Microbiol. 169:500-504 doi: 10.1016/j.resmic.2018.04.004
  • Atanasova NS, Heiniö CHE, Demina T, Bamford DH, Oksanen HM. 2018. The unexplored diversity of pleolipoviruses: the surprising case of two viruses with identical major structural modules. Genes 9:131
  • Kornilov R, Puhka M, Mannerström B, Hiidenmaa H, Peltoniemi H, Siljander P, Seppänen-Kaijansinkko R and Kaur S. "Efficient ultrafiltration-based protocol to deplete extracellular vesicles from fetal bovine serum", Journal of Extracellular Vesicles (2018) DOI:10.1080/20013078.2017.1422674
  • Pietilä MK, van Hemert MJ and Ahola T. "Purification of Highly Active Alphavirus Replication Complexes Demonstrates Altered Fractionation of Multiple Cellular Membranes", Journal of Virology (2018) DOI:10.1128/JVI.01852-17
  • Sathyanarayanan G, Haapala M, Kiiski I and Sikanen T. "Digital microfluidic immobilized cytochrome P450 reactors with integrated inkjet-printed microheaters for droplet-based drug metabolism research", Anal Bioanal Chem (2018) DOI:10.1007/s00216-018-1280-7
  • Dufurrena Q, Bäck N, Mains RE, Hodgson L, Tanowitz H, Mandela P, Eipper E and Kuliawat R. "Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion", J. Mol. Endocrinol. (2018) DOI:10.1530/JME-18-0048
  • Kaur S, Abu-Shahba AG, Paananen RO, Hongisto H, Hiidenmaa H, Skottman H, Seppänen-Kaijansinkko R and Mannerström B. "Small non-coding RNA landscape of extracellular vesicles from human stem cells", Scientific Reports (2018) DOI:10.1038/s41598-018-33899-6
  • Cenev Z, Zhang H, Sariola V, Rahikkala A, Liu D, Santos HA and Zhou Q. "Manipulating Superparamagnetic Microparticles with an Electromagnetic Needle", Advanced Materials Technologies (2018) DOI:10.1002/admt.201700177
  • Han Z, Salmi E, Vehkamäki M, Leskelä M and Ritala M. "Metal oxide multilayer hard mask system for 3D nanofabrication", Nanotechnology (2018) DOI:10.1088/1361-6528/aa9fe0
  • Gebraad A, Kornilov R, Kaur S, Miettinen S, Haimi S, Peltoniemi H, Mannerström B and Seppänen‐Kaijansinkko R. "Monocyte‐derived extracellular vesicles stimulate cytokine secretion and gene expression of matrix metalloproteinases by mesenchymal stem/stromal cells", The FEBS Journal (2018) DOI:10.1111/febs.14485
  • Olesia Ignatenko, Dmitri Chilov, Ilse Paetau, Elena de Miguel, Christopher B Jackson, Gabrielle Capin, Anders Paetau, Mugen Terzioglu, Liliya Euro and Anu Suomalainen. "Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy", Nature Communications (2018) DOI:10.1038/s41467-017-01859-9
  • Sokolova M, Moore HM, Prajapati B, Dopie J, Meriläinen L, Honkanen M, Matos RC, Poukkula M, Hietakangas V and Vartiainen MK. "Nuclear Actin Is Required for Transcription during Drosophila Oogenesis", iScience (2018) DOI:10.1016/j.isci.2018.10.010
  • Hoornstra D, Vesterlin J, Pärnänen P, Al-Samadi A, Zlotogorski-Hurvitz A, Vered M and Salo T. "Fermented Lingonberry Juice Inhibits Oral Tongue Squamous Cell Carcinoma Invasion In Vitro Similarly to Curcumin", In Vivo (Athens, Greece) (2018) DOI:10.21873/invivo.11350
  • Barok M, Puhka M, Vereb G, Szollosi J, Isola J and Joensuu H. "Cancer-derived exosomes from HER2-positive cancer cells carry trastuzumab-emtansine into cancer cells leading to growth inhibition and caspase activation", BMC Cancer (2018) DOI:10.1186/s12885-018-4418-2
  • Tähkä S, Sarfraz J, Urvas L, Provenzani R, Wiedmer SK, Peltonen J, Jokinen V and Sikanen T. "Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction.", Anal Bioanal Chem (2019) DOI:10.1007/s00216-019-01674-9

  • Zanjanizadeh NE, Shahbazi MA, Shatalin YV, Nadal E, Mäkilä E, Salonen J, Kemell M, Correia A, Hirvonen J and Santos HA. "Conductive vancomycin-loaded mesoporous silica polypyrrole-based scaffolds for bone regeneration.", Int J Pharm (2018) DOI:10.1016/j.ijpharm.2017.11.065
2017
  • Aho V, Myllys M, Ruokolainen V, Hakanen S, Mäntylä E, Virtanen J, Hukkanen V, Kühn T, Timonen J, Mattila K, Larabell CA, Vihinen-Ranta M, "Chromatin organization regulates viral egress dynamics", Sci Rep. 2017 Jun 16;7(1):3692. doi: 10.1038/s41598-017-03630-y.
  • Balasubramanian V, Correia A, Zhang H, Fontana F, Mäkilä E, Salonen J, Hirvonen J, Santos HA, “Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-like Functions”, Adv. Mater. 2017, 29(11), 1605375.
  • Bauleth-Ramos T, Shahbazi MA, Liu D, Fontana F, Correia A, Figueiredo P, Zhang H, Martins JP, Hirvonen JT, Granja P, Sarmento B, Santos HA, “Nutlin-3a and Cytokine co-loaded Spermine-modified Acetalated Dextran Nanoparticles for Cancer Chemo-immunotherapy”, Adv. Funct. Mater. 2017, 27(42), 1703303. 
  • Bäck N, Kanerva K, Kurutihalli V, Yanik A, Ikonen E, Mains RE, Eipper BA. (2017) The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together. Eur J Cell Biol. 2017 Aug;96(5):407-417. doi: 10.1016/j.ejcb.2017.03.007. Epub 2017 Mar 28.
  • Casteleijn MG, Richardson D, Parkkila P, Granqvist N, Urtti A, Viitala T, "Spin coated chitin films for biosensors and its analysis are dependent on chitin-surface interactions", Colloids and Surfaces A: Physicochemical and Engineering Aspects, Volume 539, 20 February 2018, Pages 261-272
  • Catalan J, Rydman E, Aimonen K, Hannukainen KS, Suhonen S, Vanhala E, Moreno C, Meyer V, Perez DD, Sneck A, Forsström U, Højgaard C, Willemoes M, Winther JR, Vogel U, Wolff H, Alenius H, Savolainen KM, Norppa H. (2017) Genotoxic and inflammatory effects of nanofibrillated cellulose in murine lungs. Mutagenesis. 2017 Jan;32(1):23-31. doi: 10.1093/mutage/gew035. Epub 2016 Jul 28.
  • Coloma SE, Dienstbier A, Bamford DH, Sivonen K, Roine E, Hiltunen T (2017) Newly isolated Nodularia phage influences cyanobacterial community dynamics. Environ Microbiol. 2017 Jan;19(1):273-286. doi: 10.1111/1462-2920.13601. Epub 2017 Jan 23.
  • Eskelin K, Lampi M, Meier F, Moldenhauer E, Bamford DH, Oksanen HM. (2017) Halophilic viruses with varying biochemical and biophysical properties are amenable to purification with asymmetrical flow field-flow fractionation. Extremophiles. 2017 Nov;21(6):1119-1132. doi: 10.1007/s00792-017-0963-x. Epub 2017 Oct 10.
  • Ferreira MPA, Ranjan S, Kinnunen S, Correia A, Talman V, Mäkilä E, Barrios-Lopez B, Kemell M, Balasubramanian V, Salonen J, Hirvonen J, Ruskoaho H, Airaksinen AJ, Santos HA, “Drug-loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling”, Small 2017, 13(33), 1701276
  • Figueiredo P, Lintinen K, Kiriazis A, Hynninen V, Liu Z, Bauleth Ramos T, Rahikkala A, Correia A, Kohout T, Sarmento B, Yli-Kauhaluoma J, Hirvonen J, Ikkala O, Kostiainen MA, Santos HA, “In Vitro Evaluation of Biodegradable Lignin-based Nanoparticles for Drug Delivery and Enhanced Antiproliferation Effect in Cancer Cells”, Biomaterials 2017, 121, 97–108
  • Fontana F, Shahbazi M-A, Liu D, Zhang H, Mäkilä E, Salonen J, Hirvonen JT, Santos HA, “Multistaged Nanovaccines based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy”, Adv. Mater. 2017, 29(7), 1603239.
  • Janoniene A, Liu Z, Baranauskiene L, Mäkilä E, Ma M, Salonen J, Hirvonen J, Zhang H, Petrikaite V, Santos HA, “A Versatile Carbonic Anhydrase IX Targeting Ligand Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging”, ACS Appl. Mater. Interfaces 2017, 9(16), 13976–13987.
  • Jauffrais T., LeKieffre C., Koho K.A., Tsuchiya M., Schweizer M., Bernhard J.M., Meibom A., Geslin E. (2017) Ultrastructure and distribution of kleptoplasts in benthic foraminifera from shallow-water (photic) habitats. Marine Micropaleontology in press
  • Herranz-Blanco B, Ginestar E, Zhang H, Hirvonen J, Santos HA, “Microfluidics Platform for Glass Capillaries and its Application in Droplet and Nanoparticle Fabrication”, Int. J. Pharm. 2017, 516(1-2), 100–105
  • Kerdsakundee N, Li W, Martins JP, Liu Z, Zhang F, Kemell M, Correia A, Ding Y, Airavaara M, Hirvonen J, Wiwattanapatapee R, Santos HA, “Multifunctional Nanotube–Mucoadhesive Poly(Methyl Vinyl Ether-co-maleic acid)@Hydroxypropyl Methylcellulose Acetate Succinate Composite for Site Specific Oral Drug Delivery”, Adv. Healthcare Mater. 2017, 6(20), 1700629
  • Koho K.A., LeKieffre C., Nomaki H., Salonen I., Geslin E., Mabilleau G., Søgaard Jensen L.H., Reichart G.-J. (2017) Changes in ultrastructural features of the foraminifera Ammonia spp. in response to anoxic conditions: field and laboratory observations. Marine Micropaleontology in press
  • Lalowski MM, Björk S, Finckenberg P, Soliymani R, Tarkia M, Calza G, Blokhina D, Tulokas S, Kankainen M, Lakkisto P, Baumann M, Kankuri E, Mervaala E. Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach. Front Physiol. 2018 Apr 11;9:365. doi: 10.3389/fphys.2018.00365. eCollection 2018.
  • Lauren E, Tigistu-Sahle F, Valkonen S, Westberg M, Valkeajärvi A, Eronen J, Siljander P, Pettilä V, Käkelä R, Laitinen S, Kerkelä E. (2017) Phospholipid composition of packed red blood cells and that of extracellular vesicles show a high resemblance and stability during storage. Biochim Biophys Acta. 2017 Sep 28;1863(1):1-8. doi: 10.1016/j.bbalip.2017.09.012
  • Lehti TA, Pajunen MI, Skog MS, Finne J. Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells. Nat Commun. 2017 Dec 4;8(1):1915. doi: 10.1038/s41467-017-02057-3.
  • Li W, Liu D, Zhang H, Correia A, Mäkilä E, Salonen J, Hirvonen J, Santos HA, “Microfluidic Assembly of a Nano-in-Micro Dual Drug Delivery Platform Composed of Halloysite Nanotubes and a pH-Responsive Polymer for Colon Cancer Therapy”, Acta Biomater. 2017, 48, 238–246
  • Liu Z, Balasubramanian V, Bhat C, Vahermo M, Mäkilä E, Kemell M, Fontana F, Janoniene A, Petrikaite V, Salonen J, Yli-Kauhaluoma J, Hirvonen J, Zhang H, Santos HA, “Quercetin-based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells”, Adv. Healthcare Mater. 2017, 6(3), 1601009
  • Liu D, Bernuz CR, Fan J, Li W, Correia A, Hirvonen J, Santos HA, “A Nano-in-Nano Vector: Merging the Best of Polymeric Nanoparticles and Drug Nanocrystals”, Adv. Funct. Mater. 2017, 27(9), 1604508.
  • Liu D, Zhang H, Cito S, Fan J, Mäkilä E, Salonen J, Hirvonen J, Sikanen TM, Weitz DA, Santos HA, “Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation”, Nano Lett. 2017, 17(2), 606–614.
  • Ollikainen E, Liu D, Kallio A, Mäkilä E, Zhang H, Salonen J, Santos HA, Sikanen T, “The Impact of Porous Silicon Nanoparticles on Human Cytochrome P450 Metabolism in Human Liver Microsomes In Vitro”, Eur. J. Pharm. Sci. 2017, 104, 124–132
  • Puhka M, Nordberg ME, Valkonen S, Rannikko A, Kallioniemi O, Siljander P, Af Hällström TM. KeepEX, a simple dilution protocol for improving extracellular vesicle yields from urine. Eur J Pharm Sci. 2017; 98:30-39. doi: 10.1016/j.ejps.2016.10.021
  • Puhka M, Takatalo M, Nordberg ME, Valkonen S, Nandania J, Aatonen M, Yliperttula M, Laitinen S, Velagapudi V, Mirtti T, Kallioniemi O, Rannikko A, Siljander PR, Af Hällström TM. Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes. Theranostics. 2017 Aug 23;7(16):3824-3841. doi: 10.7150/thno.19890
  • Reuter LJ, Shahbazi M-A, Mäkilä EM, Salonen JJ, Saberianfar R, Menassa R, Santos HA, Joensuu JJ, Ritala A, “Coating Nanoparticles with Plant-Produced Transferrin-Hydrophobin Fusion Protein Enhances their Uptake in Cancer Cells”, Bioconj. Chem. 2017, 28(6), 1639–1648
  • Shahbazi MA, Almeida PV, Correia A, Herranz-Blanco B, Shrestha N, Mäkilä E, Salonen J, Hirvonen J, Santos HA, “Intracellular Responsive Dual Delivery by Endosomolytic Polyplexes Carrying DNA Anchored Porous Silicon Nanoparticles”, J. Control. Release 2017, 249, 111–122.
  • Tahir N, Madni A, Balasubramanian V, Rehman M, Correia A, Kashif PM, Mäkilä E, Salonen J, Santos HA, “Development and Optimization of Methotrexate-Loaded Lipid-Polymer Hybrid Nanoparticles for Controlled Drug Delivery Applications", Int. J. Pharm. 2017, 533(1), 156–168.
  • Zhang F, Correia A, Mäkilä EM, Li W, Salonen JJ, Hirvonen J, Zhang H, Santos HA, “Receptor-Mediated Surface Charge Inversion Platform Based on Porous Silicon Nanoparticles for Efficient Cancer Cell Recognition and Combination Therapy”, ACS Appl. Mater. Interfaces 2017, 9(11), 10034–10046
2016
2015
2014
2013
  • Bimbo LM, Denisova OV, Mäkilä E, Kaasalainen M, De Brabander JK, Hirvonen J, Salonen J, Kakkola L, Kainov D, Santos HA. (2013) Inhibition of Influenza A Virus Infection in Vitro by Saliphenylhalamide-Loaded Porous Silicon Nanoparticles. ACS Nano. 2013 Aug 1. [Epub ahead of print] 
  • Douillard FP, Ribbera A, Järvinen HM, Kant R, Pietilä TE, Randazzo C, Paulin L, Laine PK, Caggia C, von Ossowski I, Reunanen J, Satokari R, Salminen S, Palva A, de Vos WM. (2013) Comparative genomic and functional analysis of Lactobacillus casei and Lactobacillus rhamnosus strains marketed as probiotics. Appl Environ Microbiol. 79(6):1923-33. doi: 10.1128/AEM.03467-12. 
  • Douillard FP, Ribbera A, Kant R, Pietilä TE, Järvinen HM, Messing M, Randazzo CL, Paulin L, Laine P, Ritari J, Caggia C, Lähteinen T, Brouns SJ, Satokari R, von Ossowski I, Reunanen J, Palva A, de Vos WM. (2013) Comparative Genomic and Functional Analysis of 100 Lactobacillus rhamnosus Strains and Their Comparison with Strain GG. PLoS Genet. 9(8):e1003683. doi: 10.1371/journal.pgen.1003683. 
  • Hedegaard SF, Nilsson C, Laurinmäki P, Butcher, S, Urtti A, Yaghmur A. (2013) Nanostructured aqueous dispersions of citrem interacting with lipids and PEGylated lipids. RSC Adv., 2013,3, 24576-24585. 
  • He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, Whistler JL, Levine B. Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism. (2013) Cell. 2013 Aug 14. doi:pii: S0092-8674(13)00943-4. 10.1016/j.cell.2013.07.035.
  • Heljo VP, Sainio J, Shevchenko A, Kivikero N, Lakio S, Juppo AM. (2013) The effect of relative humidity on the physical properties of two melibiose monohydrate batches with differing particle size distributions and surface properties. J Pharm Sci. 102(1):195-203. doi: 10.1002/jps.23366. 
  • Hetzel, U., Sironen, T., Laurinmäki, P., Liljeroos, L., Patjas, A., Henttonen, H., Vaheri, A., Artelt, A., Kipar, A., Butcher, S. J., Vapalahti, O. & Hepojoki, J. (2013) Isolation, Identification, and Characterization of Novel Arenaviruses, the Etiological Agents of Boid Inclusion Body Disease. Journal of Virology. 87, 20, p. 10918-10935. 
  • Hirvonen, S, Karesoja, M., Karjalainen, E., Hietala, S., Laurinmäki, P., Vesanen, E., Butcher, S.J., Tenhu, H. (2013) Colloidal properties and gelation of aqueous dispersions of conductive poly(benzimidazobenzophenanthroline) derivatives. Polymer 54:694-701. 
  • Kaivosoja E, Suvanto P, Barreto G, Aura S, Soininen A, Franssila S, Konttinen YT.(2013) Cell adhesion and osteogenic differentiation on three-dimensional pillar surfaces. J Biomed Mater Res A. 2013 Mar;101(3):842-52. doi: 10.1002/jbm.a.34378. 
  • Karjalainen, E., Chenna, N., Laurinmäki, P., Butcher, S.J., Tenhu H. (2013) Diblock copolymers consisting of polymerized ionic liquid and poly(N-isopropylacrylamide). Effects of PNIPAM block length and counter ion on self-assembling and thermal properties. Polym.Chem. 4:1014-1024. 
  • Lehti S, Käkelä R, Hörkkö S, Kummu O, Helske-Suihko S, Kupari M, Werkkala K, Kovanen PT, Öörni K.(2013) Modified lipoprotein-derived lipid particles accumulate in human stenotic aortic valves. PLoS One. 8:e65810. 
  • Li L, Sillanpää M, Tuominen M, Lounatmaa K, Schultz E.(2013) Behavior of titanium dioxide nanoparticles in Lemna minor growth test conditions. Ecotoxicol Environ Saf. 2013 Feb;88:89-94. doi: 10.1016/j.ecoenv.2012.10.024. 
  • Liljeroos, L., Krzyzaniak, M. A., Helenius, A., Butcher, S. (2013) Architecture of respiratory syncytial virus revealed by electron cryotomography. Proceedings of the National Academy of Sciences of the United States of America. 110, 27, s. 11133-11138. 
  • Liu D, Bimbo LM, Mäkilä E, Villanova F, Kaasalainen M, Herranz-Blanco B, Caramella CM, Lehto VP, Salonen J, Herzig KH, Hirvonen J, Santos HA. (2013) Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles. J Control Release. 170(2):268-78. doi: 10.1016/j.jconrel.2013.05.036. 
  • Malinovskaja, K., Laaksonen, T., Kontturi , K., Hirvonen, J. (2013) Ion-exchange and iontophoresis-controlled delivery of apomorphine, Eur. J. Pharm. Biopharm. 83(3) 477-484. 
  • Mori MM, Airaksinen AJ, Hirvonen JT, Santos HA, Caramella CM. (2013) Evaluation of the physicochemical and biopharmaceutical properties of fluoro-indomethacin. Curr Drug Metab. 14(1):80-9. 
  • Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S.J., Raki, M., Bergström, K., Weng Larsen, S., Řstergaard, J., Larsen, C., Urtti, A., Airaksinen, A., Yaghmur, A. (2013) SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications. Biomaterials 34:8491-8503. 
  • Noro A, Sillat T, Virtanen I, Ingerpuu S, Bäck N, Konttinen YT, Korhonen M. (2013) Laminin production and basement membrane deposition by mesenchymal stem cells upon adipogenic differentiation. J Histochem Cytochem. 2013 Oct;61(10):719-30. doi: 10.1369/0022155413502055. 
  • Penkina A, Antikainen O, Hakola M, Vuorinen S, Repo T, Yliruusi J, Veski P, Kogermann K, Heinämäki J. (2013) Direct Compression of Cellulose and Lignin Isolated by a New Catalytic Treatment. AAPS PharmSciTech. 2013 Jul 19. [Epub ahead of print] 
  • Pessi T, Karhunen V, Karjalainen PP, Ylitalo A, Airaksinen JK, Niemi M, Pietila M, Lounatmaa K, Haapaniemi T, Lehtimäki T, Laaksonen R, Karhunen PJ, Mikkelsson J.(2013) Bacterial signatures in thrombus aspirates of patients with myocardial infarction. Circulation. 2013 Mar 19;127(11):1219-28, e1-6. doi: 10.1161/CIRCULATIONAHA.112.001254. 
  • Pietilä MK, Atanasova NS, Oksanen HM, Bamford DH.(2013) Modified coat protein forms the flexible spindle-shaped virion of haloarchaeal virus His1. Environ Microbiol. 2013 Jun;15(6):1674-86. doi: 10.1111/1462-2920.12030. 
  • Pietilä, M.K., Laurinmäki, P., Russell, D.A., Ko, C., Jacobs-Sera, D., Butcher, S.J., Bamford, D.H., Hendrix, R.W. (2013) Insights into head-tailed viruses infecting extremely halophilic archaea. J. Virol. 87:3248-3260. 
  • Pietilä, M.K., Laurinmäki, P., Russell, D.A., Ko, C., Jacobs-Sera, D., Hendrix, R.W., Bamford, D.H., Butcher, S.J. (2013) Structure of the archaeal head-tailed virus HSTV-1 completes the HK97 fold story. PNAS 110(26), 10604-10609. 
  • Pietiäinen V, Vassilev B, Blom T, Wang W, Nelson J, Bittman R, Bäck N, Zelcer N, Ikonen E. (2013) NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation. J Cell Sci. 2013 Jul 10. [Epub ahead of print] 
  • Pšencik, J., Arellano, J.M., Collins, A.M., Laurinmäki, P., Torkkeli, M., Löflund, B., Serimaa, R.E., Blankenship, R.E., Tuma, R., Butcher, S.J. (2013) Structure and functional role of carotenoids in chlorosomes. J. Bact 195: 1727-1734. 
  • Raula, J., Rahikkala, A., Halkola, T., Pessi, J., Peltonen, L., Hirvonen, J., Järvinen, K., Laaksonen, T., Kauppinen, E.I. (2013) Coated particle assemblies for the concomitant pulmonary administration of budesonide and salbutamol sulphate, Int. J. Pharm. 441(1-2) 248-€254. 
  • Revez J, Schott T, Llarena AK, Rossi M, Hänninen ML. (2013) Genetic heterogeneity of Campylobacter jejuni NCTC 11168 upon human infection. Infect Genet Evol. 16:305-9. doi: 10.1016/j.meegid.2013.03.009. 
  • Rosenqvist K, Airaksinen S, Fraser SJ, Gordon KC, Juppo AM.(2013) Interaction of bioactive glass with clodronate. Int J Pharm. 2013 Aug 16;452(1-2):102-7. doi: 10.1016/j.ijpharm.2013.04.059. 
  • Schneppenheim J, Dressel R, Hüttl S, Lüllmann-Rauch R, Engelke M, Dittmann K, Wienands J, Eskelinen EL, Hermans-Borgmeyer I, Fluhrer R, Saftig P, Schröder B. (2013) The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain. J Exp Med. 210(1):41-58. 
  • Shahbazi MA, Hamidi M, Mäkilä EM, Zhang H, Almeida PV, Kaasalainen M, Salonen JJ, Hirvonen JT, Santos HA. (2013) The mechanisms of surface chemistry effects of mesoporous silicon nanoparticles on immunotoxicity and biocompatibility. Biomaterials. 34(31):7776-89. doi: 10.1016/j.biomaterials.2013.06.052. 
  • Shakeel S., Seitsonen, J., Kajander, T., Laurinmäki, P., Hyypiä, T., Susi, P., Butcher, S.J. (2013) Structural and functional analysis of coxsackievirus A9 receptor binding and uncoating. J. Virol. /87:3943-3951. 
  • Sun X., Pirttimaa M.J., Bamford D.H., Poranen M.M., (2013) Rescue of Maturation Off-Pathway Products in the Assembly of Pseudomonas Phage phi6. J Virol 87(24), 13279-13286. 
  • Tamminen K, Lappalainen S, Huhti L, Vesikari T, Blazevic V. (2013) Trivalent combination vaccine induces broad heterologous immune responses to norovirus and rotavirus in mice. PLoS One. 8(7):e70409. doi: 10.1371/journal.pone.0070409. 
  • Valo H., Arola S., Laaksonen P., Torkkeli M., Peltonen L., Linder M.B., Serimaa R., Kuga S., Hirvonen J., Laaksonen T., Drug Release from Nanoparticles Embedded in Four Different Nanofibrillar Cellulose Aerogels, Eur. J. Pharm. Sci., accepted for publication. 
  • von Ossowski I, Pietilä TE, Rintahaka J, Nummenmaa E, Mäkinen VM, Reunanen J, Satokari R, de Vos WM, Palva I, Palva A. (2013) Using recombinant Lactococci as an approach to dissect the immunomodulating capacity of surface piliation in probiotic Lactobacillus rhamnosus GG. PLoS One. 8(5):e64416. doi: 10.1371/journal.pone.0064416.Bimbo LM, Denisova OV, Mäkilä E, Kaasalainen M, De Brabander JK, Hirvonen J, Salonen J, Kakkola L, Kainov D, Santos HA. (2013) Inhibition of Influenza A Virus Infection in Vitro by Saliphenylhalamide-Loaded Porous Silicon Nanoparticles. ACS Nano. 2013 Aug 1. [Epub ahead of print] 
  • Douillard FP, Ribbera A, Järvinen HM, Kant R, Pietilä TE, Randazzo C, Paulin L, Laine PK, Caggia C, von Ossowski I, Reunanen J, Satokari R, Salminen S, Palva A, de Vos WM. (2013) Comparative genomic and functional analysis of Lactobacillus casei and Lactobacillus rhamnosus strains marketed as probiotics. Appl Environ Microbiol. 79(6):1923-33. doi: 10.1128/AEM.03467-12. 
  • Douillard FP, Ribbera A, Kant R, Pietilä TE, Järvinen HM, Messing M, Randazzo CL, Paulin L, Laine P, Ritari J, Caggia C, Lähteinen T, Brouns SJ, Satokari R, von Ossowski I, Reunanen J, Palva A, de Vos WM. (2013) Comparative Genomic and Functional Analysis of 100 Lactobacillus rhamnosus Strains and Their Comparison with Strain GG. PLoS Genet. 9(8):e1003683. doi: 10.1371/journal.pgen.1003683. 
  • Hedegaard SF, Nilsson C, Laurinmäki P, Butcher, S, Urtti A, Yaghmur A. (2013) Nanostructured aqueous dispersions of citrem interacting with lipids and PEGylated lipids. RSC Adv., 2013,3, 24576-24585. 
  • He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, Whistler JL, Levine B. Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism. (2013) Cell. 2013 Aug 14. doi:pii: S0092-8674(13)00943-4. 10.1016/j.cell.2013.07.035.
  • Heljo VP, Sainio J, Shevchenko A, Kivikero N, Lakio S, Juppo AM. (2013) The effect of relative humidity on the physical properties of two melibiose monohydrate batches with differing particle size distributions and surface properties. J Pharm Sci. 102(1):195-203. doi: 10.1002/jps.23366. 
  • Hetzel, U., Sironen, T., Laurinmäki, P., Liljeroos, L., Patjas, A., Henttonen, H., Vaheri, A., Artelt, A., Kipar, A., Butcher, S. J., Vapalahti, O. & Hepojoki, J. (2013) Isolation, Identification, and Characterization of Novel Arenaviruses, the Etiological Agents of Boid Inclusion Body Disease. Journal of Virology. 87, 20, p. 10918-10935. 
  • Hirvonen, S, Karesoja, M., Karjalainen, E., Hietala, S., Laurinmäki, P., Vesanen, E., Butcher, S.J., Tenhu, H. (2013) Colloidal properties and gelation of aqueous dispersions of conductive poly(benzimidazobenzophenanthroline) derivatives. Polymer 54:694-701. 
  • Kaivosoja E, Suvanto P, Barreto G, Aura S, Soininen A, Franssila S, Konttinen YT.(2013) Cell adhesion and osteogenic differentiation on three-dimensional pillar surfaces. J Biomed Mater Res A. 2013 Mar;101(3):842-52. doi: 10.1002/jbm.a.34378. 
  • Karjalainen, E., Chenna, N., Laurinmäki, P., Butcher, S.J., Tenhu H. (2013) Diblock copolymers consisting of polymerized ionic liquid and poly(N-isopropylacrylamide). Effects of PNIPAM block length and counter ion on self-assembling and thermal properties. Polym.Chem. 4:1014-1024. 
  • Lehti S, Käkelä R, Hörkkö S, Kummu O, Helske-Suihko S, Kupari M, Werkkala K, Kovanen PT, Öörni K.(2013) Modified lipoprotein-derived lipid particles accumulate in human stenotic aortic valves. PLoS One. 8:e65810. 
  • Li L, Sillanpää M, Tuominen M, Lounatmaa K, Schultz E.(2013) Behavior of titanium dioxide nanoparticles in Lemna minor growth test conditions. Ecotoxicol Environ Saf. 2013 Feb;88:89-94. doi: 10.1016/j.ecoenv.2012.10.024. 
  • Liljeroos, L., Krzyzaniak, M. A., Helenius, A., Butcher, S. (2013) Architecture of respiratory syncytial virus revealed by electron cryotomography. Proceedings of the National Academy of Sciences of the United States of America. 110, 27, s. 11133-11138. 
  • Liu D, Bimbo LM, Mäkilä E, Villanova F, Kaasalainen M, Herranz-Blanco B, Caramella CM, Lehto VP, Salonen J, Herzig KH, Hirvonen J, Santos HA. (2013) Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles. J Control Release. 170(2):268-78. doi: 10.1016/j.jconrel.2013.05.036. 
  • Malinovskaja, K., Laaksonen, T., Kontturi , K., Hirvonen, J. (2013) Ion-exchange and iontophoresis-controlled delivery of apomorphine, Eur. J. Pharm. Biopharm. 83(3) 477-484. 
  • Mori MM, Airaksinen AJ, Hirvonen JT, Santos HA, Caramella CM. (2013) Evaluation of the physicochemical and biopharmaceutical properties of fluoro-indomethacin. Curr Drug Metab. 14(1):80-9. 
  • Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S.J., Raki, M., Bergström, K., Weng Larsen, S., Řstergaard, J., Larsen, C., Urtti, A., Airaksinen, A., Yaghmur, A. (2013) SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications. Biomaterials 34:8491-8503. 
  • Noro A, Sillat T, Virtanen I, Ingerpuu S, Bäck N, Konttinen YT, Korhonen M. (2013) Laminin production and basement membrane deposition by mesenchymal stem cells upon adipogenic differentiation. J Histochem Cytochem. 2013 Oct;61(10):719-30. doi: 10.1369/0022155413502055. 
  • Penkina A, Antikainen O, Hakola M, Vuorinen S, Repo T, Yliruusi J, Veski P, Kogermann K, Heinämäki J. (2013) Direct Compression of Cellulose and Lignin Isolated by a New Catalytic Treatment. AAPS PharmSciTech. 2013 Jul 19. [Epub ahead of print] 
  • Pessi T, Karhunen V, Karjalainen PP, Ylitalo A, Airaksinen JK, Niemi M, Pietila M, Lounatmaa K, Haapaniemi T, Lehtimäki T, Laaksonen R, Karhunen PJ, Mikkelsson J.(2013) Bacterial signatures in thrombus aspirates of patients with myocardial infarction. Circulation. 2013 Mar 19;127(11):1219-28, e1-6. doi: 10.1161/CIRCULATIONAHA.112.001254. 
  • Pietilä MK, Atanasova NS, Oksanen HM, Bamford DH.(2013) Modified coat protein forms the flexible spindle-shaped virion of haloarchaeal virus His1. Environ Microbiol. 2013 Jun;15(6):1674-86. doi: 10.1111/1462-2920.12030. 
  • Pietilä, M.K., Laurinmäki, P., Russell, D.A., Ko, C., Jacobs-Sera, D., Butcher, S.J., Bamford, D.H., Hendrix, R.W. (2013) Insights into head-tailed viruses infecting extremely halophilic archaea. J. Virol. 87:3248-3260. 
  • Pietilä, M.K., Laurinmäki, P., Russell, D.A., Ko, C., Jacobs-Sera, D., Hendrix, R.W., Bamford, D.H., Butcher, S.J. (2013) Structure of the archaeal head-tailed virus HSTV-1 completes the HK97 fold story. PNAS 110(26), 10604-10609. 
  • Pietiäinen V, Vassilev B, Blom T, Wang W, Nelson J, Bittman R, Bäck N, Zelcer N, Ikonen E. (2013) NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation. J Cell Sci. 2013 Jul 10. [Epub ahead of print] 
  • Pšencik, J., Arellano, J.M., Collins, A.M., Laurinmäki, P., Torkkeli, M., Löflund, B., Serimaa, R.E., Blankenship, R.E., Tuma, R., Butcher, S.J. (2013) Structure and functional role of carotenoids in chlorosomes. J. Bact 195: 1727-1734. 
  • Raula, J., Rahikkala, A., Halkola, T., Pessi, J., Peltonen, L., Hirvonen, J., Järvinen, K., Laaksonen, T., Kauppinen, E.I. (2013) Coated particle assemblies for the concomitant pulmonary administration of budesonide and salbutamol sulphate, Int. J. Pharm. 441(1-2) 248-€254. 
  • Revez J, Schott T, Llarena AK, Rossi M, Hänninen ML. (2013) Genetic heterogeneity of Campylobacter jejuni NCTC 11168 upon human infection. Infect Genet Evol. 16:305-9. doi: 10.1016/j.meegid.2013.03.009. 
  • Rosenqvist K, Airaksinen S, Fraser SJ, Gordon KC, Juppo AM.(2013) Interaction of bioactive glass with clodronate. Int J Pharm. 2013 Aug 16;452(1-2):102-7. doi: 10.1016/j.ijpharm.2013.04.059. 
  • Schneppenheim J, Dressel R, Hüttl S, Lüllmann-Rauch R, Engelke M, Dittmann K, Wienands J, Eskelinen EL, Hermans-Borgmeyer I, Fluhrer R, Saftig P, Schröder B. (2013) The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain. J Exp Med. 210(1):41-58. 
  • Shahbazi MA, Hamidi M, Mäkilä EM, Zhang H, Almeida PV, Kaasalainen M, Salonen JJ, Hirvonen JT, Santos HA. (2013) The mechanisms of surface chemistry effects of mesoporous silicon nanoparticles on immunotoxicity and biocompatibility. Biomaterials. 34(31):7776-89. doi: 10.1016/j.biomaterials.2013.06.052. 
  • Shakeel S., Seitsonen, J., Kajander, T., Laurinmäki, P., Hyypiä, T., Susi, P., Butcher, S.J. (2013) Structural and functional analysis of coxsackievirus A9 receptor binding and uncoating. J. Virol. /87:3943-3951. 
  • Sun X., Pirttimaa M.J., Bamford D.H., Poranen M.M., (2013) Rescue of Maturation Off-Pathway Products in the Assembly of Pseudomonas Phage phi6. J Virol 87(24), 13279-13286. 
  • Tamminen K, Lappalainen S, Huhti L, Vesikari T, Blazevic V. (2013) Trivalent combination vaccine induces broad heterologous immune responses to norovirus and rotavirus in mice. PLoS One. 8(7):e70409. doi: 10.1371/journal.pone.0070409. 
  • Valo H., Arola S., Laaksonen P., Torkkeli M., Peltonen L., Linder M.B., Serimaa R., Kuga S., Hirvonen J., Laaksonen T., Drug Release from Nanoparticles Embedded in Four Different Nanofibrillar Cellulose Aerogels, Eur. J. Pharm. Sci., accepted for publication. 
  • von Ossowski I, Pietilä TE, Rintahaka J, Nummenmaa E, Mäkinen VM, Reunanen J, Satokari R, de Vos WM, Palva I, Palva A. (2013) Using recombinant Lactococci as an approach to dissect the immunomodulating capacity of surface piliation in probiotic Lactobacillus rhamnosus GG. PLoS One. 8(5):e64416. doi: 10.1371/journal.pone.0064416.
2012
  • Aalto AP, Bitto D, Ravantti JJ, Bamford DH, Huiskonen JT, Oksanen HM.(2012) Snapshot of virus evolution in hypersaline environments from the characterization of a membrane-containing Salisaeta icosahedral phage 1. Proc Natl Acad Sci U S A. 2012 May 1;109(18):7079-84. doi: 10.1073/pnas.1120174109. 
  • Atanasova NS, Roine E, Oren A, Bamford DH, Oksanen HM.(2012) Global network of specific virus-host interactions in hypersaline environments. Environ Microbiol. 2012 Feb;14(2):426-40. doi: 10.1111/j.1462-2920.2011.02603.x. 
  • Bimbo LM, Sarparanta M, Mäkilä E, Laaksonen T, Laaksonen P, Salonen J, Linder MB, Hirvonen J, Airaksinen AJ, Santos HA. (2012) Cellular interactions of surface modified nanoporous silicon particles. Nanoscale 4(10):3184-92. doi: 10.1039/c2nr30397c. 
  • Dearborn, A.D., Laurinmäki, P., Chandramouli, P., Rodenburg, C.M., Wang, S., Butcher, S.J., Dokland, T. (2012) Structure and size determination of bacteriophage P2 and P4 procapsids: function of size responsiveness mutations. J. Struct. Biol. 178:215-224. 
  • Cascone A, Bruelle C, Lindholm D, Bernardi P, Eriksson O. (2012) Destabilization of the outer and inner mitochondrial membranes by core and linker histones. PLoS One. 7(4):e35357. doi: 10.1371/journal.pone.0035357. 
  • Claes IJ, Schoofs G, Regulski K, Courtin P, Chapot-Chartier MP, Rolain T, Hols P, von Ossowski I, Reunanen J, de Vos WM, Palva A, Vanderleyden J, De Keersmaecker SC, Lebeer S. (2012) Genetic and biochemical characterization of the cell wall hydrolase activity of the major secreted protein of Lactobacillus rhamnosus GG. PLoS One. 7(2):e31588. doi: 10.1371/journal.pone.0031588. 
  • Ding WX, Li M, Biazik JM, Morgan DG, Guo F, Ni HM, Goheen M, Eskelinen EL, Yin XM. (2012) Electron microscopic analysis of a spherical mitochondrial structure. J Biol Chem. 287(50):42373-8. 
  • Finckenberg P, Eriksson O, Baumann M, Merasto S, Lalowski MM, Levijoki J, Haasio K, Kytö V, Muller DN, Luft FC, Oresic M, Mervaala E. (2012) Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy. Hypertension. 59(1):76-84. 
  • Gruetzner H, Ellor JW, Back N.(2012) Identifiable grief responses in persons with Alzheimer's disease. J Soc Work End Life Palliat Care. 2012;8(2):151-64. doi: 10.1080/15524256.2012.685439. 
  • Heljo VP, Nordberg A, Tenho M, Virtanen T, Jouppila K, Salonen J, Maunu SL, Juppo AM. (2012) The effect of water plasticization on the molecular mobility and crystallization tendency of amorphous disaccharides. Pharm Res. 29(10):2684-97. doi: 10.1007/s11095-011-0658-4. 
  • Kaivosoja E, Suvanto P, Barreto G, Aura S, Soininen A, Franssila S, Konttinen YT. (2012) Cell adhesion and osteogenic differentiation on three-dimensional pillar surfaces. J Biomed Mater Res A. 2012 Sep 11. doi: 10.1002/jbm.a.34378. 
  • Koho, T., Huhti, L., Blazevic, V., Nurminen, K., Butcher, S.J., Laurinmäki, P., Kalkkinen, N., Rönnholm, G., Vesikari, T., Hytönen, V.P., Kulomaa, M.S. (2012) Production and characterization of virus-like particles and the P domain protein of GII.4 norovirus. J. Vir. Methods 179:1-7. 
  • Koho, T., Mäntylä,T., Laurinmäki, P., Huhti, L. Butcher, S., Vesikari,T., Kulomaa, M.S., Hytönen, V.P. (2012) Purification of norovirus-like particles (VLPs) by ion exchange chromatography. J. Vir. Methods. 181:6-11. 
  • Kolakovic, R., Laaksonen, T., Peltonen, L., Laukkanen, A., Hirvonen J. (2012) Spray-dried nanofibrillar cellulose microparticles for sustained drug release, Int. J. Pharm. 430(1-2) 47-55. 
  • Kolakovic, R., Peltonen, L., Laukkanen, A., Hirvonen J., Laaksonen, T. (2012) Nanofibrillar cellulose films for controlled drug release, Eur. J. Pharm. Biopharm. 82(2) 308-315. 
  • Kuronen M, Hermansson M, Manninen O, Zech I, Talvitie M, Laitinen T, Gröhn O, Somerharju P, Eckhardt M, Cooper JD, Lehesjoki AE, Lahtinen U, Kopra O. (2012). Galactolipid deficiency in the early pathogenesis of neuronal ceroid lipofuscinosis model Cln8mnd : implications to delayed myelination and oligodendrocyte maturation. Neuropathol Appl Neurobiol. 38(5):471-86. doi: 10.1111/j.1365-2990.2011.01233.x. 
  • Lebeer S, Claes I, Tytgat HL, Verhoeven TL, Marien E, von Ossowski I, Reunanen J, Palva A, Vos WM, Keersmaecker SC, Vanderleyden J. (2012) Functional analysis of Lactobacillus rhamnosus GG pili in relation to adhesion and immunomodulatory interactions with intestinal epithelial cells. Appl Environ Microbiol. 78(1):185-93. doi: 10.1128/AEM.06192-11. 
  • Li J, Brader G, Helenius E, Kariola T, Palva ET. (2012) Biotin deficiency causes spontaneous cell death and activation of defense signaling. Plant J. 70(2):315-26. doi: 10.1111/j.1365-313X.2011.04871.x. 
  • Myllymaa S, Kaivosoja E, Myllymaa K, Sillat T, Korhonen H, Lappalainen R, Konttinen YT.(2012) Adhesion, spreading and osteogenic differentiation of mesenchymal stem cells cultured on micropatterned amorphous diamond, titanium, tantalum and chromium coatings on silicon. J Mater Sci Mater Med. 2010 Jan;21(1):329-41. doi: 10.1007/s10856-009-3836-8. 
  • Nguyen SD, Öörni K, Lee-Rueckert M, Pihlajamaa T, Metso J, Jauhiainen M, Kovanen PT. Spontaneous remodeling of HDL particles at acidic pH enhances their capacity to induce cholesterol efflux from human macrophage foam cells. J Lipid Res. 2012 Oct;53(10):2115-25. Epub 2012 Aug 1. 
  • Partanen JI, Tervonen TA, Myllynen M, Lind E, Imai M, Katajisto P, Dijkgraaf GJ, Kovanen PE, Mäkelä TP, Werb Z, Klefström J. (2012) Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):E388-97. Epub 2012 Jan 20. 
  • Pietilä, MK, Atanasova, NS, Manole, V, Liljeroos, L., Butcher, SJ, Oksanen, HM, Bamford, DH. (2012) Virion architecture unifies globally distributed pleolipoviruses infecting halophilic archaea. J. Virol, 86:5067-5079. 
  • Rautio M, Sipponen A, Lohi J, Lounatmaa K, Koukila-Kähkölä P, Laitinen K.(2012) In vitro fungistatic effects of natural coniferous resin from Norway spruce (Picea abies). Eur J Clin Microbiol Infect Dis. 2012 Aug;31(8):1783-9. doi: 10.1007/s10096-011-1502-9. 
  • Reunanen J, von Ossowski I, Hendrickx AP, Palva A, de Vos WM. (2012) Characterization of the SpaCBA pilus fibers in the probiotic Lactobacillus rhamnosus GG. Appl Environ Microbiol. 78(7):2337-44. doi: 10.1128/AEM.07047-11. 
  • Sarin, L.P, Hirvonen, J., Laurinmäki, P., Butcher, S.J., Bamford, D.H., Poranen, M.M. (2012) Bacteriophage φ6 nucleocapsid surface protein 8 interacts with virus-specific membrane vesicles containing the major envelope protein 9. J. Virol. 86:5376-5379. 
  • Sedlak M: Homopolymer Self-assembly into Stable Nanoparticles: Concerted Action of Hydrophobic Association and Hydrogen Bonding in Thermoresponsive Poly(alkylacrylic acid)s, J. Phys. Chem. B, 116 (8), 2356–2364, 2012. 
  • Seitsonen, J., Shakeel, S., Susi, P., Pandurangan, A., Sinkovits, R.S., Hyvönen, H., Laurinmäki, P., Ylä-Pelto, J., Topf, M., Hyypiä, T., Butcher, S.J. (2012) Structural analysis of coxsackievirus A7 reveals conformational changes associated with uncoating. J. Virol. 86:7207-7215. 
  • Skurnik, M., Hyytiäinen, H., Happonen, L., Kiljuenn, S., Datta, N., Mattinen, L., Williamson, K., Kristo, P., Szeliga, M., Kalin-Mänttätri, L., Ahola-Iivarinen, E., Kalkkinen, N., Butcher S.J. (2012) Characterization of the genome, proteome and structure of yersiniophage φR1-37. J. Virol. 86:12625-12642. 
  • Tamminen K, Huhti L, Koho T, Lappalainen S, Hytönen VP, Vesikari T, Blazevic V. (2012) A comparison of immunogenicity of norovirus GII-4 virus-like particles and P-particles. Immunology. 135(1):89-99. doi: 10.1111/j.1365-2567.2011.03516.x. 
  • Vale N, Mäkilä E, Salonen J, Gomes P, Hirvonen J, Santos HA. (2012) New times, new trends for ethionamide: In vitro evaluation of drug-loaded thermally carbonized porous silicon microparticles. Eur J Pharm Biopharm. 81(2):314-23. doi: 10.1016/j.ejpb.2012.02.017.
2011
  • Alhoranta, A., Lehtinen, J., Urtti, A., Butcher, S.J., Aseyev, V., Tenhu, H. (2011) Cationic amphiphilic star and linear block copolymers: synthesis, self-assembly and in vitro gene transfection. Biomacromolecules 12:3213. 
  • Behnke J, Eskelinen EL, Saftig P, Schröder B. (2011) Two dileucine motifs mediate late endosomal/lysosomal targeting of transmembrane protein 192 (TMEM192) and a C-terminal cysteine residue is responsible for disulfide bond formation in TMEM192 homodimers. Biochem J. 2011 Mar 1;434(2):219-31. 
  • Bimbo, L.M., Mäkilä, E., Laaksonen, T., Lehto, V.-P., Salonen, J., Hirvonen, J., Santos, H.A. (2011) Drug permeation across intestinal epithelial cells using porous silicon nanoparticles, Biomaterials 32(10) 2625-2633. 
  • Blazevic V, Lappalainen S, Nurminen K, Huhti L, Vesikari T. (2011) Norovirus VLPs and rotavirus VP6 protein as combined vaccine for childhood gastroenteritis. Vaccine. 29(45):8126-33. doi: 10.1016/j.vaccine.2011.08.026. 
  • Dichlberger, A., Schlager, S., Lappalainen, J., Käkelä, R., Hattula, K., Butcher, S.J., Schneider, W.J., Kovanen, P.T. (2011) Lipid body formation during maturation of human mast cells. J. Lipid Research 52:2198-2208. 
  • Eskelinen EL, Reggiori F, Baba M, Kovacs AL, Seglen PO.(2011) Seeing is believing: the impact of electron microscopy on autophagy research. Autophagy 7(9):935-56. 
  • Kerminen, V.-M., Niemi, J.V., Timonen, H., Aurela, M., Frey, A., Caborone, S., Saarikoski, S., Teinilä, K., Hakkarainen, J., Tamminen, J., Vira, J., Prank, M., Sofiev, M., Hillamo, R. (2011) Characterization of a volcanic ash episode in southern Finland caused by the Grimsvötn eruption in Iceland in May 2011. Atmospheric Chemistry and Physics 11, 12227-12239. 
  • Kinnari P, Mäkilä E, Heikkilä T, Salonen J, Hirvonen J, Santos HA. (2011) Comparison of mesoporous silicon and non-ordered mesoporous silica materials as drug carriers for itraconazole. Int J Pharm. 414(1-2):148-56. 
  • Kumar, V., Butcher, S.J., Öörni, K., Engelhardt, P., Heikkonen, J., Kaski, K., Ala-Korpela, M., Kovanen, P.T. (2011) Three-dimensional cryoEM reconstruction of native LDL particles to 16 Å resolution at physiological body temperature. PLoS ONE 6(5): e18841. 
  • Laaksonen, T., Liu, P., Rahikkala, A., Peltonen, L., Kauppinen, E.I., Hirvonen, J., Järvinen, K., Raula, J. (2011) Intact Nanoparticulate Indomethacin in Fast Dissolving Carrier Particles by Combined Wet Milling and Aerosol Flow Reactor Methods, Pharm. Res. 28(10) 2403-2411. 
  • Leo, J.C., Lyskowski A., Hattula, K., Hartmann, M.,Schwarz, H., Butcher, S.J., Linke, D., Lupas, A.N., Goldman, A. (2011) The structure of E. coli IgG-binding protein D suggests a general model for bending and binding in trimeric autotransporter adhesins. Structure doi:10.1016/j.str.2011.03.021. 
  • Liljeroos, L., Huiskonen, J., Ora, A., Susi, P., Butcher, S.J. (2011) Electron cryotomography of measles virus reveals that matrix protein coats the ribonucleocapsid within intact virions. Proc. Natl. Acad. Sci. (USA) 108:18085-90. 
  • Liu P., Rong, X., Hirvonen, J., Laaksonen, T., Peltonen, L. (2011) Nanosuspension of poorly soluble drugs: preparation and development by wet milling, Int. J. Pharm. 411 215-222. 
  • Mattila M, Lindström M, Somervuo P, Markkula A, Korkeala H. (2011) Role of flhA and motA in growth of Listeria monocytogenes at low temperatures. Int J Food Microbiol.148(3):177-83. doi: 10.1016/j.ijfoodmicro.2011.05.022. 
  • O'Connell Motherway M, Zomer A, Leahy SC, Reunanen J, Bottacini F, Claesson MJ, O'Brien F, Flynn K, Casey PG, Munoz JA, Kearney B, Houston AM, O'Mahony C, Higgins DG, Shanahan F, Palva A, de Vos WM, Fitzgerald GF, Ventura M, O'Toole PW, van Sinderen D. (2011) Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor. Proc Natl Acad Sci U S A. 108(27):11217-22. doi: 10.1073/pnas.1105380108. 
  • Paloheimo O, Ihalainen TO, Tauriainen S, Välilehto O, Kirjavainen S, Niskanen EA, Laakkonen JP, Hyöty H, Vihinen-Ranta M. (2011) Coxsackievirus B3-induced cellular protrusions: structural characteristics and functional competence. J Virol. 85(13):6714-24. doi: 10.1128/JVI.00247-10. 
  • Valo, H., Kovalainen, M., Laaksonen, P., Häkkinen, M., Auriola, S., Peltonen, L., Linder, M., Järvinen, K., Hirvonen J., Laaksonen, T. (2011) Immobilization of protein-coated drug nanoparticles in nanofibrillar cellulose matrices - enhanced stability and release, J. Controlled Release 156(3) 390-397. 
  • Varjonen, S., Laaksonen, P., Paananen, A., Valo, H., Hähl, H., Laaksonen, T., Linder, M.B. (2011) Self-Assembly of Cellulose Nanofibrils by Genetically Engineered Fusion Proteins, Soft Matter 7 2402-2411. 
  • von Ossowski I, Satokari R, Reunanen J, Lebeer S, De Keersmaecker SC, Vanderleyden J, de Vos WM, Palva A. (2011) Functional characterization of a mucus-specific LPXTG surface adhesin from probiotic Lactobacillus rhamnosus GG. Appl Environ Microbiol. 77(13):4465-72. doi: 10.1128/AEM.02497-10.
2010
  • Bimbo, L.M., Sarparanta, M., Santos, H.A., Airaksinen, A.J., Mäkilä, E., Laaksonen, T., Peltonen, L., Lehto, V.-P., Hirvonen, J., Salonen, J. (2010) Biocompatibility of Thermally Hydrocarbonized Porous Silicon Nanoparticles and their Biodistribution in Rats, ACS Nano 4(6) 3023-3032. 
  • Blom T, Bäck N, Mutka A-L, Bittman R, Li Z, de Lera A, Kovanen PT, Diczfalusy U, Ikonen E (2010) FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages Circulation Research 106:720-729. 
  • Broholm SK, Pöllänen E, Ruokolainen S, Tähtiharju S, Kotilainen M, Albert VA, Elomaa P, Teeri TH. (2010) Functional characterization of B class MADS-box transcription factors in Gerbera hybrida. J Exp Bot. 61(1):75-85. doi: 10.1093/jxb/erp279. 
  • Bäck N, Rajagopal C, Mains RE, Eipper BA (2010) Secretory granule membrane protein recycles through multivesicular bodies Traffic 11:972-986. 
  • Cvirkaite-Krupovic V, Krupovic M, Daugelavicius R, Bamford DH.(2010) Calcium ion-dependent entry of the membrane-containing bacteriophage PM2 into its Pseudoalteromonas host. Virology. 2010 Sep 15;405(1):120-8. doi: 10.1016/j.virol.2010.05.021. 
  • Genina N, Räikkönen H, Ehlers H, Heinämäki J, Veski P, Yliruusi J.(2010). Thin-coating as an alternative approach to improve flow properties of ibuprofen powder.Int J Pharm. 2010 Mar 15;387(1-2):65-70. doi: 10.1016/j.ijpharm.2009.12.005. 
  • Genina N, Räikkönen H, Heinämäki J, Veski P, Yliruusi J. (2010) Nano-coating of beta-galactosidase onto the surface of lactose by using an ultrasound-assisted technique. AAPS PharmSciTech. 2010 Jun;11(2):959-65. doi: 10.1208/s12249-010-9462-4. 
  • Happonen, L.J. Redder, P., Peng, X., Reigstad, L.J., Prangishvili, D., Butcher, S.J. (2010) Familial relationships in hyperthermo- and acidophilic archaeal viruses. J. Virol. 84:4747-4754. 
  • Hepojoki, J., Strandin, T., Vaheri, A., Lankinen, H. (2010) Interactions and oligomerization of hantavirus glycoproteins. J Virol 84, 227-242. 
  • Huhti L, Blazevic V, Nurminen K, Koho T, Hytönen VP, Vesikari T (2010) A comparison of methods for purification and concentration of norovirus GII-4 capsid virus-like particles. Arch Virol. 155(11):1855-8. 
  • Huiskonen, J.T., Hepojoki, J., Laurinmäki, P., Vaheri, A., Lankinen. H., Butcher, S.J., Grunewald, K. (2010) Electron cryo-tomography of tula hantavirus suggests a unique assembly paradigm for enveloped viruses. J. Virol. 84:4889-4897. 
  • Kaivosoja E, Myllymaa S, Kouri VP, Myllymaa K, Lappalainen R, Konttinen YT. (2010) Enhancement of silicon using micro-patterned surfaces of thin films. Eur Cell Mater. 2010 Apr 9;19:147-57. 
  • Kanerva K, Mäkitie LT, Bäck N, Andersson LC (2010) Ornithine decarboxylase antizyme inhibitor 2 regulates intracellular vesicle trafficking Experimental Cell Research 316:1896-1906. 
  • Krick R, Bremer S, Welter E, Schlotterhose P, Muehe Y, Eskelinen EL, Thumm M. (2010) Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8. J Cell Biol. 190(6):965-73. 
  • Mervaala E, Biala A, Merasto S, Lempiäinen J, Mattila I, Martonen E, Eriksson O, Louhelainen M, Finckenberg P, Kaheinen P, Muller DN, Luft FC, Lapatto R, Oresic M. (2010) Metabolomics in angiotensin II-induced cardiac hypertrophy. Hypertension. 55(2):508-15. 
  • Michon F, Tummers M, Kyyrönen M, Frilander MJ, Thesleff I. (2010) Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 340(2):355-68. doi: 10.1016/j.ydbio.2010.01.019. 
  • Myllymaa S, Kaivosoja E, Myllymaa K, Sillat T, Korhonen H, Lappalainen R, Konttinen YT. (2010) Adhesion, spreading and osteogenic differentiation of mesenchymal stem cells cultured on micropatterned amorphous diamond, titanium, tantalum and chromium coatings on silicon. J Mater Sci Mater Med. 2010 Jan;21(1):329-41. Epub 2009 Aug 5. 
  • Paasonen, L. Sipilä, T., Subrizi, A., Laurinmäki, P., Butcher, S.J., Rappolt, M., Yaghmur, A., Urtti, A., Yliperttula, M. (2010) Gold-embedded photosensitive liposomes for drug delivery: triggering mechanism and intracellular release. J. Controlled Release 147:136-143 
  • Pietilä MK, Laurinavicius S, Sund J, Roine E, Bamford DH.(2010) The single-stranded DNA genome of novel archaeal virus halorubrum pleomorphic virus 1 is enclosed in the envelope decorated with glycoprotein spikes. J Virol. 2010 Jan;84(2):788-98. doi: 10.1128/JVI.01347-09. 
  • Rintala J-M, Hällfors H, Hällfors S, Hällfors G, Majaneva M, Blomster J (2010) Heterocapsa arctica subsp. frigida subsp. nov. (Peridiniales, Dinophyceae) - description of a new dinoflagellate and its occurrence in the Baltic sea. J. Phycol. 46, 751-762. 
  • Roine E, Kukkaro P, Paulin L, Laurinavicius S, Domanska A, Somerharju P, Bamford DH.(2010) New, closely related haloarchaeal viral elements with different nucleic Acid types. J Virol. 2010 Apr;84(7):3682-9. doi: 10.1128/JVI.01879-09. 
  • Romano S, D'Angelillo A, Pacelli R, Staibano S, De Luna E, Bisogni R, Eskelinen EL, Mascolo M, Cali G, Arra C, Romano MF (2010) Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells, Cell Death Differ. 17(1):145-57. 
  • Seitsonen, J., Susi, P., Heikkilä, O., Sinkovits, R.S., Laurinmäki, P., Hyypiä, T., Butcher, S.J. (2010). Interaction of αVβ3 and αVβ6 integrins with Human parechovirus 1. J. Virol 84:8509-8519. 
  • Seppälä K, Heinämäki J, Hatara J, Seppälä L, Yliruusi J.(2010) Development of a new method to get a reliable powder flow characteristics using only 1 to 2 g of powder AAPS PharmSciTech. 2010 Mar;11(1):402-8. doi: 10.1208/s12249-010-9397-9. 
  • Törmäkangas L, Markkula E, Lounatmaa K, Puolakkainen M.(2010) Chlamydia pneumoniae infection in polarized epithelial cell lines. Infect Immun. 2010 Jun;78(6):2714-22. doi: 10.1128/IAI.01456-09. 
  • Valo, H., Laaksonen, P., Peltonen, L., Linder, M.B., Hirvonen, J., Laaksonen, T. (2010) Multifunctional Hydrophobin: Toward Functional Coatings for Drug Nanoparticles, ACS Nano 4(3) 1750–1758. 
  • Virtanen S, Antikainen O, Räikkönen H, Yliruusi J. (2010) Granule size distribution of tablets. J Pharm Sci. 99(4):2061-9. doi: 10.1002/jps.21945. 
  • Zhou Y, Li S, Mäyränpää MI, Zhong W, Bäck N, Yan D, Olkkonen VM (2010) OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface Experimental Cell Research 316:3304-3316.
2009
  • Ehlers H, Räikkönen H, Antikainen O, Heinämäki J, Yliruusi J.(2009) Improving flow properties of ibuprofen by fluidized bed particle thin-coating. Int J Pharm. 2009 Feb 23;368(1-2):165-70. doi: 10.1016/j.ijpharm.2008.10.013. 
  • Ehlers H, Liu A, Räikkönen H, Hatara J, Antikainen O, Airaksinen S, Heinämäki J, Lou H, Yliruusi J.(2009) Granule size control and targeting in pulsed spray fluid bed granulation. Int J Pharm. 2009 Jul 30;377(1-2):9-15. doi: 10.1016/j.ijpharm.2009.04.041 
  • Genina N, Räikkönen H, Heinämäki J, Antikainen O, Siiriä S, Veski P, Yliruusi J.(2009) Effective modification of particle surface properties using ultrasonic water mist. AAPS PharmSciTech. 2009;10(1):282-8. doi: 10.1208/s12249-009-9208-3. 
  • Hynynen R, Suchanek M, Spandl J, Bäck N, Thiele C, Olkkonen VM (2009) OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids. J Lipid Res. 50(7):1305-15. 
  • Palgi M, Lindström R, Peränen J, Piepponen TP, Saarma M, Heino TI.(2009) Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2429-34. doi: 10.1073/pnas.0810996106. 
  • Pietilä MK, Roine E, Paulin L, Kalkkinen N, Bamford DH.(2009) An ssDNA virus infecting archaea: a new lineage of viruses with a membrane envelope. Mol Microbiol. 2009 Apr;72(2):307-19. doi: 10.1111/j.1365-2958.2009.06642.x. 
  • Polianskyte Z, Peitsaro N, Dapkunas A, Liobikas J, Soliymani R, Lalowski M, Speer O, Seitsonen J, Butcher S, Cereghetti GM, Linder MD, Merckel M, Thompson J, Eriksson O. (2009) LACTB is a filament-forming protein localized in mitochondria. Proc Natl Acad Sci U S A. 106(45):18960-5. doi: 10.1073/pnas.0906734106. 
  • Rantalainen KI, Christensen PA, Hafren A, Otzen DE, Kalkkinen N, Mäkinen K. (2009) Interaction of a potyviral VPg with anionic phospholipid vesicles. Virology 395(1):114-20. doi: 10.1016/j.virol.2009.09.009. 
  • Saarikangas J, Zhao H, Pykäläinen A, Laurinmäki P, Mattila PK, Kinnunen PK, Butcher SJ, Lappalainen P. (2009) Molecular mechanisms of membrane deformation by I-BAR domain proteins. Curr Biol. 19(2):95-107. 
  • Shikov AN, Pozharitskaya ON, Miroshnyk I, Mirza S, Urakova IN, Hirsjärvi S, Makarov VG, Heinämäki J, Yliruusi J, Hiltunen R (2009) Nanodispersions of taxifolin: impact of solid-state properties on dissolution behavior.Int J Pharm. 2009 Jul 30;377(1-2):148-52. doi: 10.1016/j.ijpharm.2009.04.044. 
  • Sipponen A, Peltola R, Jokinen JJ, Laitinen K, Lohi J, Rautio M, Mannisto M, Sipponen P, Lounatmaa K.(2009) Effects of Norway spruce (Picea abies) resin on cell wall and cell membrane of Staphylococcus aureus. Ultrastruct Pathol. 2009;33(3):128-35. doi: 10.1080/01913120902889138. 
  • Sobota JA, Bäck N, Eipper BA, Mains RE (2009) Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory- pathway proteins. J. Cell Sci, 22(Pt 19):3542-53. 
  • Valo H, Peltonen L, Vehviläinen S, Karjalainen M, Kostiainen R, Laaksonen T, Hirvonen J. (2009) Electrospray encapsulation of hydrophilic and hydrophobic drugs in poly(L-lactic acid) nanoparticles. Small. 5(15):1791-8. doi: 10.1002/smll.200801907
2008
  • Helle A, Hirsjärvi S, Peltonen S, Hirvonen J, Wiedmer SK. (2008). Quantitative determination of drug encapsulation in poly(lactic acid) nanoparticles by capillary electrophoresis. J Chromatography A 1178:248-255. 
  • Hirsjärvi S, Peltonen L, Hirvonen J. (2008). Surface pressure measurements in particle interaction and stability studies of poly(lactic acid) nanoparticles. Int J pharmaceutics 348:153-160. 
  • Kukkola E., Saranpää P. and Fagerstedt K.V. (2008) Juvenile and compression wood cell wall layers differ in lignin structure in Norway spruce and Scots pine. IAWA journal 29: 47-54. 
  • Lindén MV, Meinander K, Helle A, Yohannes G, Riekkola M-L, Butcher SJ, Viitala T, Wiedmer SK (2008). Characterization of phosphatidylcholine/polyethylene glycol-lipid aggregates and their use as coatings and carriers in capillary electrophoresis. Electrophoresis, in press 
  • Saarikangas J, Hakanen J, Mattila PK, Grumet M, Salminen M, Lappalainen P (2008). ABBA regulates plasma-membrane and actin dynamics to promote radial glial extensions. J Cell Sci 121:1444-1454. 
  • Seitsonen JJT, Susi P, Lemmetty A, Butcher SJ (2008). Structure of the mite-transmitted Blackcurrant reversion nepovirus using electron cryo-microscopy. Virology 278:162-168. 
  • Tammela T, Zarkada G, Wallgard E, Murtomäki A, Suchting S, Wirzenius M, Waltari M, Hellström M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Ylä-Herttuala S, Shibuya M, Pytowski B, Eichmann A, Betsholtz C, Alitalo K. (2008). Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 07083 doi:10.1038 
  • Wang Q, Cuellar WJ, Rajamäki M-L, Hirata Y., Valkonen JPT. (2008). Combined thermotherapy and cryotherapy for efficient virus eradication: relation of virus distribution, subcellular changes, cell survival and viral RNA degradation in shoot tips. Mol Plant Path 9:237-250.
2007
  • Gaidelyte A, Vaara M, Bamford DH. (2007). Bacteria, Phages and Septicemia. PLos ONE 2(11):e1145, doi:10.1371/journal.pone.0001145. 
  • Huiskonen JT, Jaalinoja HT, Briggs JA, Fuller SD, Butcher SJ. (2007). Structure of a hexameric RNA packaging motor in a viral polymerase complex. J Struct Biol 158:156-164. 
  • Huiskonen JT, Manole V, Butcher SJ. (2007). Tale of two spikes in bacteriophage PRD1. Proc Natl Acad Sci U S A 104:6666-6671. 
  • Ikonen TP, Li H, Psencik J, Laurinmaki PA, Butcher SJ, Frigaard NU, Serimaa RE, Bryant DA, Tuma R. (2007). X-ray scattering and electron cryomicroscopy study on the effect of carotenoid biosynthesis to the structure of Chlorobium tepidum chlorosomes. Biophys J 93:620-628. 
  • Jaalinoja HT, Huiskonen JT, Butcher SJ. (2007). Electron cryomicroscopy comparison of the architectures of the enveloped bacteriophages phi6 and phi8. Structure 15:157-167. 
  • Karhu NJ, Ziedaite G, Bamford DH, Bamford JK. (2007). Efficient DNA packaging of bacteriophage PRD1 requires the unique vertex protein P6. J Virol 81:2970-2979. 
  • Krupovic M, Daugelavicius R, Bamford DH. (2007). A novel lysis system in PM2, a lipid-containing marine double-stranded DNA bacteriophage. Mol Microbiol 64:1635-1648. 
  • Marjamaa K., Kukkola E.M. and Fagerstedt K.V. (2007) Lignification in development. Int J Plant Dev Biol 1: 160-169. (Invited review) 
  • Rintala J-M, Spilling K, Blomster J. (2007). Temporary cyst enables long-term dark survival of Scrippsiella hangoei (Dinophyceae). Mar Biol 152:57-62. 
  • Jonna Saarimaki-Vire, Paula Peltopuro,Laura Lahti, Thorsten Naserke, Alexandra A. Blak, Daniela M. Vogt Weisenhorn, Kai Yu, David M. Ornitz, Wolfgang Wurst, and Juha Partanen (2007). Fibroblast Growth Factor Receptors Cooperate to Regulate Neural Progenitor Properties in the Developing Midbrain and Hindbrain. J Neurosci 27:8581-8592. 
  • Strandman S., Zarembo A., Darinskii A.A., Löflund B, Butcher S.J., Tenhu,H. (2007). Self-assembling of star-like amphiphilic block copolymers with polyelectrolyte blocks. Effect of pH. Polymer 48:7008-7016. 
  • Wang QC, Valkonen J. (2007). Efficient elimination of sweetpotato little leaf phytoplasma from sweetpotato by cryotherapy of shoot tips. Plant pathology. Doi:10.1111/j.1365-3059.2007.01710.x
2006
  • Hirsjärvi S, Peltonen L, Hirvonen J. (2006). Layer-by-layer polyelectrolyte coating of low molecular weight poly(lactic acid) nanoparticles. Colloids and Surfaces B: Biointerfaces 49:93-99. 
  • Huiskonen JT, de Haas F, Bubeck D, Bamford DH, Fuller SD, Butcher SJ. (2006). Structure of the bacteriophage phi6 nucleocapsid suggests a mechanism for sequential RNA packaging. Structure 14:1039-1048. 
  • Kivela HM, Roine E, Kukkaro P, Laurinavicius S, Somerharju P, Bamford DH. (2006). Quantitative dissociation of archaeal virus SH1 reveals distinct capsid proteins and a lipid core. Virology 356:4-11. 
  • Laitinen, R.A.E., Broholm, S., Albert, V.A., Teeri, T.H. and Elomaa, P. (2006). Patterns of MADS-box gene expression mark flower-type development in Gerbera hybrida (Asteraceae). BMC Plant Biology 6:11. 
  • Marjamaa K., Hilden K., Kukkola E., Lehtonen M., Holkeri H., Haapaniemi P., Teeri T., Koutaniemi S., Teeri T.H., Fagerstedt K. and Lundell T. (2006). Cloning, characterization and localisation of three novel class III peroxidases in lignifying xylem of Norway spruce (Picea abies). Plant Mol Biol 61: 719-732. 
  • Niemi K, Baumann MH, Kovanen PT, Eklund KK. (2006) Serum amyloid A (SAA) activates human mast cells which leads into degradation of SAA and generation of an amyloidogenic SAA fragment. Biochim Biophys Acta. 1762:424-30. 
  • Psencik J, Arellano JB, Ikonen TP, Borrego CM, Laurinmaki PA, Butcher SJ, Serimaa RE, Tuma R. (2006). Internal structure of chlorosomes from brown-colored chlorobium species and the role of carotenoids in their assembly. Biophys J 91:1433-1440. 
  • Strandman S, Hietala S, Koli B, Butcher SJ, Tenhu H. (2006). Supramolecular assemblies of amphiphilic PMMA-b-PAA stars in aqueous solutions. Polymer 47:6524-6535. 
  • Torrance, L., Andreev, I.A., Gabrenaite-Verkhovskaya, R., Cowan, G., Mäkinen, K. and Taliansky, M.E. (2006). An unusual structure at one end of potato potyvirus particles. J Mol Biol 357:1-8.
2005
  • Briggs JA, Huiskonen JT, Fernando KV, Gilbert RJ, Scotti P, Butcher SJ, Fuller SD. (2005). Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles. J Struct Biol 150:332-339. 
  • Daugelavicius R, Cvirkaite V, Gaidelyte A, Bakiene E, Gabrenaite-Verkhovskaya R, Bamford DH. (2005). Penetration of Enveloped Double-Stranded RNA Bacteriophages phi13 and phi6 into Pseudomonas syringae Cells. J Virol 79:5017-5026. 
  • Gaidelyte A, Jaatinen ST, Daugelavicius R, Bamford JK, Bamford DH. (2005). The linear double-stranded DNA of phage Bam35 enters lysogenic host cells, but the late phage functions are suppressed. J Bacteriol 187:3521-3527. 
  • Hyvönen S, Peltonen L, Karjalainen M, Hirvonen J. (2005) Effect of nanoprecipitation on the physicochemical properties of low molecular weight poly(L-lactic acid) nanoparticles loaded with salbutamol sulphate and beclomethasone dipropionate. Int j Pharmaceutics 295:269-281. 
  • Laurinmaki PA, Huiskonen JT, Bamford DH, Butcher SJ. (2005). Membrane proteins modulate the bilayer curvature in the bacterial virus bam35. Structure 13:1819-1828. 
  • Lehto M, Hynynen R, Karjalainen K, Kuismanen E, Hyvärinen K, Olkkonen VM. (2005). Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants. Exp Cell Res. 310:445-62. 
  • Liu XL, Kilpeläinen P, Hellman U, Sun Y, Wartiovaara J, Morgunova E, Pikkarainen T,Yan K, Jonsson AP, Tryggvason K. (2005). Characterization of the interactions of the nephrin intracellular domain. FEBS J. 272: 228-243. 
  • Merckel MC, Huiskonen JT, Bamford DH, Goldman A, Tuma R. (2005). The Structure of the Bacteriophage PRD1 Spike Sheds Light on the Evolution of Viral Capsid Architecture. Mol Cell 18:161-170. 
  • Porter K, Kukkaro P, Bamford JK, Bath C, Kivela HM, Dyall-Smith ML, Bamford DH. (2005). SH1: A novel, spherical halovirus isolated from an Australian hypersaline lake. Virology 335:22-33. 
  • Stoecker D, Autio R, Rintala J-M, Kuosa H. (2005). Ecto-cellular enzyme activity associated with filamentous cyanobacteria. Aquatic microbial ecology 40:151-161. 
  • Tryggvason K, Wartiovaara J. (2005) How does the kidney filter plasma? Physiology. 20: 96-101. 
  • öörni K., Posio P., Ala-Korpela M., Jauhiainen M.& Kovanen P.T. (2005) Sphingomyelinase induces aggregation and fusion of small very low-density lipoprotein and intermediate-density lipoprotein particles and increases their retention to human arterial proteoglycans. Arterioscler Thromb Vasc Biol 25:1678-83.
2004
  • Abrescia NG, Cockburn JJ, Grimes JM, Sutton GC, Diprose JM, Butcher SJ, Fuller SD, San Martin C, Burnett RM, Stuart DI, Bamford DH, Bamford JK. (2004). Insights into assembly from structural analysis of bacteriophage PRD1. Nature 432:68-74. 
  • Hakulinen J, Junnikkala S, Sorsa T, Meri S. (2004) Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to functionally active soluble form. Eur J Immunol 34:2620-2629. 
  • Huiskonen JT, Kivela HM, Bamford DH, Butcher SJ. (2004). The PM2 virion has a novel organization with an internal membrane and pentameric receptor binding spikes. Nat Struct Mol Biol 11:850-856. 
  • Jaatinen ST, Viitanen SJ, Bamford DH, Bamford JK. (2004). Integral membrane protein P16 of bacteriophage PRD1 stabilizes the adsorption vertex structure. J Virol 78:9790-9797. 
  • Kivela HM, Daugelavicius R, Hankkio RH, Bamford JK, Bamford DH. (2004). Penetration of membrane-containing double-stranded-DNA bacteriophage PM2 into Pseudoalteromonas hosts. J Bacteriol 186:5342-5354.
  • Kukkola E.M., Koutaniemi S., Pöllänen E., Gustafsson M., Karhunen P., Lundell T.K., Saranpää P., Kilpeläinen I., Teeri T.H. and Fagerstedt K.V. (2004). Dibenzodioxocin lignin substructure is abundant in inner part of secondary wall in Norway spruce and silver birch xylem. Planta 218:497-500. 
  • Kumar, V., Heikkonen, J., Engelhardt, P. and Kaski, K. (2004). Robust filtering and particle picking in micrograph images towards 3D reconstruction of purified proteins with cryo-electron microscopy. J Struct Biol, 145:41-51. 
  • Lahdenkari, A.-T., Lounatmaa, K., Patrakka, J., Holmberg, C., Wartiovaara, J., Kestilä, M., Koskimies, O., and Jalanko, H. (2004) Podocytes are firmly attached to glomerular basement membrane in kidneys with heavy proteinuria. J. Am. Soc. Nephrol. 15:2611-2618. 
  • Mäyränpää M, Simpanen J., Hess MW, Werkkala K, Kovanen P. (2004). Arterial endothelial denudation by intraluminal use of papaverine-NaCl solution in coronary bypass surgery. Eur J Cardio-thoracic surgery 25:560-566. 
  • Nuopponen, M., Ojala, J. and Tenhu, H. (2004). Aggregation behaviour of well defined amphiphilic diblock copolymers with poly(N-isopropylacrylamide) and hydrophobic blocks. Polymer, 45:3643-3650. 
  • Peltonen L, Aitta J, Hyvönen S, Karjalainen M, Hirvonen J. (2004) Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(l)lactide nanoparticles. AAPS PharmSciTech 5, article 16 
  • Psencik J, Ikonen TP, Laurinmaki P, Merckel MC, Butcher SJ, Serimaa RE, Tuma R. (2004). Lamellar organization of pigments in chlorosomes, the light harvesting complexes of green photosynthetic bacteria. Biophys J 87:1165-1172. 
  • Salgado PS, Makeyev EV, Butcher SJ, Bamford DH, Stuart DI, Grimes JM. (2004). The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure 12: 307-316. 
  • Wartiovaara, J., Öfverstedt, L.-G., Khoshnoodi, J., Zhang, J., Mäkelä, E., Sandin, S., Ruotsalainen, V., Cheng, H., Jalanko, H., Skoglund U., and Tryggvason, K. (2004). Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography. J. Clin. Invest. 114:1475-1483. 
  • Öörni K., Sneck M., Brömme D., Pentikäinen M.O., Lindstedt K.A., Mäyränpää M., Aitio H.& Kovanen P.T. (2004) Cysteine protease cathepsin F is expressed in human atherosclerotic lesions, is secreted by cultured macrophages, and modifies low density lipoprotein particles in vitro. J Biol Chem 279:34776-84.