Liisa Holm: Bioinformatics

We develop computational methods to compare and classify data pouring out from genome sequencing and structural genomics projects. For example, we have developed an ultrafast database search method which enables high-throughput functional and taxonomic assignment as well as error detection and correction based on a consensus over homologues. We have expertise in big data, data science, evolutionary classification, and software development.

Our main research directions are:

  • Development and evaluation of methods for multiclass multi-label classification tasks exemplified by automated function prediction (AFP)
  • Functional and taxonomic identification applied to genomes, metagenomes, and antimicrobial resistance (AMR)
  • Structural bioinformatics (Dali server)

Read more about the group's research:

Contact

Liisa Holm, PhD
Professor, PI
Institute of Biotechnology, HiLIFE

Biocenter 2, room 4005
P.O. Box 56 (Viikinkaari 5D)
00014 University of Helsinki
Finland

liisa.holm@helsinki.fi