We are studying the formation and homeostasis of corneal epithelium in physiological and pathological contexts. Our aspiration is to decipher the genetic network sustaining the maintenance of corneal epithelium to propose new regenerative medicine strategies for patients facing corneal blindness.
We focus on the steps leading stem cell fate determination and on the molecular cues that trigger their homing to the niche. Moreover, we unravel the factors, which either maintain the stemness or lead to cell differentiation, and how this network is modulated during aging, genetic defects and/or upon corneal trauma.
Frederic Michon, PhD
Institute of Biotechnology, HiLIFE
P.O. Box 56 (Viikinkaari 5D)
00014 University of Helsinki
Phone:+356 2 941 59491
Frederic is a Principal Investigator/Associate Group Leader at BI and Principal Investigator at INSERM, Institute of Neurosciences in Montpellier, France.