Developmental and functional specification of stem cells

Anamaria Balic research group

Adult tissue homeostasis and repair is regulated by stem cells found both within the tissue and recruited from outside the organ. The timing and mechanism governing niche formation and stem cell specification are not known, and similarly, little is known about the regulation of homing and migration of stem cells to the site of injury. To address these fundamental questions in stem cell biology we utilize the continuously growing incisor tooth model whose continuous growth is supported by lifelong maintenance of epithelial stem cells, and stable influx of mesenchymal stem cells. We combine state of the art genomic, cellular, and molecular biology approaches in order to unravel the mechanisms which regulate these stem cell populations during early development and in postnatal life.


Anamaria Balic, MD, PhD
Senior Researcher
Institute of Biotechnology, HiLIFE

Biocenter 2
P.O. Box 56 (Viikinkaari 5D)
00014 University of Helsinki

Phone:  +358 29 41 59655

Anamaria is an Principal Investigator/Associate Group Leader at BI and a Principal Investigator at the Center of Dental Medicine, University of Zurich.