Mass Spectrometry and Metabolomics

The research focus of the Mass spectrometry and metabolomics group involves the development of novel and more sensitive, selective and faster LC-MS and GC-MS methods for the analysis of drugs and biomolecules, as well as their metabolites in biological samples, such as urine, blood, and brain tissue by using various mass spectrometry techniques. The group is specialized in the development of novel ionization techniques including ionization microchips for ultra-trace analysis, atmospheric pressure photoionization methods for the analysis of nonpolar compounds and ambient mass spectrometry for fast analysis. The novel technologies are utilized in metabolism research and metabolomics even at single cell level that provides unique insights into the physiological effects of diseases, drugs, toxicants or genetic alternations. Unit's principal investigators are listed below.