After Carroll, 1988 and McKenna & Bell, 1997

<==o †Xenungulata [Pyrotheria]
   |-- †Carodnia [Ctalecarodnia] [Carodniidae]
   |--o †Colombitheriidae
   |  |-- †Colombitherium Hoffstetter, 1970
   |  `-- †Proticia Patterson, 1977
   `--o †Pyrotheriidae Ameghino, 1889
      |?- †Carolozittelia [not recognized by Shockey & Anaya Daza, 2004]
      |-- †Griphodon Anthony, 1924
      |-- †Propyrotherium Ameghino, 1901
      `--o †Pyrotherium Ameghino, 1889
         |-- †P. romeroi Ameghino, 1889
         `-- †P. macfaddeni Shockey & Anaya Daza, 2004

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