After McKenna & Bell, 1997 and de Muizon, McDonald, Salas & Urbina, 2003, 2004

    Nothrotheriidae Ameghino, 1920 sensu de Muizon, McDonald, Salas & Urbina, 2004

        Nothrotherinae Ameghino, 1920
        Megalonychidae: Nothrotherinae Ameghino; Kraglievich, 1923
        Megalonychidae: Nothrotheriinae Ameghino; Simpson, 1945
        Megatheriidae? Nothrotheriinae Ameghino; Patterson & Pascual, 1968, 1972
        Megatheriidae: Nothrotheriinae Ameghino; Paula Couto, 1981
        Megatheriidae: Nothrotheriinae Ameghino; Engelmann, 1985
        Megatheriidae: Nothrotheriinae Ameghino; Patterson et al., 1992
        Nothrotheriidae Ameghino; Gaudin, 1994
        Megatheriidae: Megatheriinae: Nothrotheriini Ameghino; McKenna & Bell, 1997
        Nothrotheriidae Ameghino; Gaudin & De Iuliis, 1999
        Nothrotheriidae Ameghino; de Muizon, McDonald, Salas & Urbina, 2004

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