|
||||||||||
| Home | Contact Info | Research Activities | Members | Publications | In Situ Unit | Links | Pictures | |||
|
||||||||||
| Home | Contact Info | Research Activities | Members | Publications | In Situ Unit | Links | Pictures | |||
Selected Publications
|
SELECTED ORIGINAL ARTICLES 2008 Hytönen, M.K., Grall, A., Hédan, B., Dréano S., Seguin S.J., Delattre, D., Thomas, A., Galibert, F., Paulin, L., Lohi, H., Sainio, K., André, C. Ancestral T-Box Mutation Is Present in Many, but Not All, Short-Tailed Dog Breeds. J. Hered. Oct 14. [Epub ahead of print], 2008.
Drögemüller, C., Karlsson, E.K., Hytönen, M.K., Perloski, M., Dolf, G., Sainio, K., Lohi, H., Lindblad-Toh, K., Leeb, T. A. Mutation in Hairless Dogs Implicates FOXI3 in Ectodermal Development. Science, 12:1462, 2008. Häyry, V., Tanner, M., Blom, T., Tynninen, O., Roselli, A., Ollikainen, M., Sariola, H., Wartiovaara, K., Nupponen, N.N. Copy number alterations of the polycomb gene BMI1 in gliomas. Acta Neuropathol., 116:97-102, 2008.
Vivatbutsiri, P., Ichinose, S., Hytönen, M., Sainio, K., Iseki, S. Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxc1 mutant. J. Anat., 212:603-611, 2008.
Bridgewater, D., Cox, B., Cain, J., Lau, A., Athaide, V., Gill, P.S., Kuure, S., Sainio, K., Rosenblum, N.D. Canonical WNT/beta-catenin signaling is required for ureteric branching. Dev. Biol., 317:83-94, 2008.
Häyry, V., Tynninen, O., Haapasalo, H.K., Wölfer, J., Paulus, W., Hasselblatt, M., Sariola, H., Paetau, A., Sarna, S., Niemelä, M., Wartiovaara, K., Nupponen, N.N. Stem cell protein BMI-1 is an independent marker for poor prognosis in oligodendroglial tumours. Neuropathol. Appl. Neurobiol. 34:555-563, 2008.
Immonen, T., Alakuijala, A., Hytönen, M., Sainio, K., Poteryaev, D., Saarma, M., Pasternack, M., Sariola, H. A proGDNF-related peptide BEP increases synaptic excitation in rat hippocampus. Exp. Neurol., 210:793-796, 2008.
2007
Kuure, S., Popsueva,
A., Jakobson, M., Sainio, K and Sariola, H. GSK3 inactivation and
stabilisation of b-catenin induce nephron
2006 Piltti. K., Kerosuo, L., Hakanen, J., Eriksson, M., Angers-Loustau, A., Leppä, S., Salminen, M., Sariola, H. and Wartiovaara, K. E6/E7 oncogenes increase and tumor suppressors decrease the proportion of self-renewing neural progenitor cells. Oncogene, 25:4880-9, 2006. 2005 Kuure, S., Sainio, K., Vuolteenaho, R., Ilves, M., Wartiovaara, K., Immonen, T., Kvist, J., Vainio, S. and Sariola, H. Crosstalk between Jagged1 and GDNF/Ret/GFRa1 signalling regulates ureteric budding and branching. Mech. Dev., 122:765-780, 2005. Perälä, N.M., Immonen, T., and Sariola, H. The expression of plexins during mouse embryogenesis.Gene Expr. Patterns 5:355-62, 2005. 2004 Arighi E., Popsueva, A., Innocenti, D. Borrello, M.G., Carniti, C., Perälä, N.M.,. Pierotti, M.A., and Sariola, H. Biological effects of the dual phenotypic Janus mutation of ret co-segregating with both multiple endocrine neoplasia type 2 and Hirschsprung’s disease. Mol. Endocrinol. 18:1004-17, 2004. 2003 Popsueva, A., Poteryaev, D., Arighi, E., Meng, X., Angers-Loustau, A., Kaplan, D., Saarma, M., Sariola, H. GDNF induces phosphorylation of Met and tubulogenesis of GFRa1-expressing MDCK cells via c-Src. J. Cell Biol. 161:119-129, 2003 2002 Meng, X., Akutsu, H., Schoene, K., Reifsteck, C., Fox, EP., Olson, S., Sariola, H., Yanagimachi, R., Baetscher, M. Transgene insertion induced dominant male sterility and rescue of male fertility using round spermatid injection. Biol. Reprod. 66:726-734, 2002 Meng, X., Wahlström, G., Immonen, T., Kolmer, M., Tirronen, M., Predel, R., Kalkkinen, N., Heino, T., Sariola, H., Roos, C. The Drosophila hugin gene codes for myostimulatory and ecdysis-modifying neuropeptides. Mech. Devel. 117:5-13, 2002 Shen, L., Pichel, J.G., Mayeli, T., Sariola, H., Lu, B., Westphal, H. Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice. Am. J. Hum. Genet. 70:435-47, 2002 2001 Meng, X., de Rooij, D., Westerdahl, K., Saarma, M., Sariola, H. Promotion of seminomatous tumours by targeted overexpression of glial cell line-derived neurotrophic factor. Cancer Res. 61:3267-3271, 2001 Meng, X., Pata, I., Pedrono, E., Popsueva, A., de Rooij, D., Jänne, M., Rauvala, H., Sariola, H. Transient disruption of spermatogenesis by deregulated expression of neurturin in testis. Molec. Cellul. Endocrinol. 183:33-39, 2001 2000 Meng, X., Lindahl, M., Salo, M., Raatikainen-Ahokas, A., Wartiovaara, K., Westerdahl, K., Parvinen, M., Rauvala, H., Lakso, M., Pichel, G., Westphal, H., Saarma, M., Sariola, H. Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science, 287:1489-1493, 2000 Raatikainen-Ahokas, A., Hytönen M., Tenhunen, A., Sariola, H. BMP-4 affects the ureteric branching, maintains the metanephric mesenchyme and reveals an early anterior-posterior axis in the embryonic kidney. Devel. Dyn. 217:146-159, 2000 Raatikainen-Ahokas, A., Immonen, T., Rossi, P., Sainio, K., Sariola, H. An artifactual in situ hybridization signal associates with apoptosis in rat embryo. J. Histochem. Cytochem. 48:955-61, 2000 1998 Elomaa, O., Sankala, M., Pikkarainen, T., Bergmann, U., Tuuttila, A., Raatikainen-Ahokas, A., Sariola, H., Tryggvason, K. Structure of the human macrophage MARCO receptor and characterization of its bacteria-binding region. J. Biol. Chem. 273:4530-4538, 1998 1997 Sainio K. Hellstedt P. Kreidberg J. Saxén L Sariola H. Differential regulation of two sets of mesonephric tubules by WT-1. Development 124:1293-1299, 1997 Sanford L. Ormsby I. Gittenberger de Groot A. Friedman R. Sariola H. Boivin G. Cardell E. Doetschman T. Transforming Growth Factor b2 TGFb2 knockout mice have multiple developmental defects that are nonoverlapping with other TGFb knockout phenotypes. Development 124:2659-2670, 1997 Suvanto, P., Wartiovaara, K., Lindahl, M., Sariola, H., Saarma, M. Cloning, distribution and chromosomal localisation of human GDNFRb gene, a homolog of GDNFRa. Human Mol. Gen. 6:1267-1273, 1997. Sainio, K., Suvanto, P., Davies, J., Wartiovaara, J., Wartiovaara, K., Saarma, M., Arumäe, U., Meng X., Lindahl, M., Pachnis, V., Sariola, H. Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 124: 4077 - 4087 1997 1996 Pichel JG. Shen L. Sheng HZ. Granholm AC. Drago J. Grinberg A. Lee EJ. Huang SP. Saarma M. Hoffer BJ. Sariola H. Westphal H. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382:73-76, 1996. Durbec P. Marcos-Gutierrez C. Kilkenny C. Grigoriou M. Wartiovaara K. Suvanto P. Smith D. Ponder B. Costantini F. Saarma M. Sariola H. Pachnis V. GDNF signalling through the Ret receptor tyrosine kinase. Nature 381:789-793, 1996 Trupp M. Arena E. Fainzilber M. Nilsson A.-S. Sieber B.A. Grigoriou M. Kilkenny C. Salazar-Grueso E. Pachnis V. Arumäe U. Sariola H. Saarma M. Ibánez C. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381:785-789, 1996 1995 Karavanov A. Sainio K. Palgi J. Saarma M. Saxén L. Sariola H. Neurotrophin 3 rescues neuronal precursors from apoptosis and promotes neuronal differentiation in the embryonic metanephric kidney. Proc. Nat. Acad. Sci. (USA). 92:11279-11283, 1995. 1993 Kreidberg JA. Sariola H. Loring JM. Maeda M. Pelletier J. Housman D. Jaenisch R. WT-1 is required for early kidney development. Cell 74:679-691, 1993. 1991 Sariola H. Saarma M. Sainio K. Arumae U. Palgi J. Vaahtokari A. Thesleff I. Karavanov A. Dependence of kidney morphogenesis on the expression of nerve growth factor receptor. Science 254:571-573, 1991. 1989 Sariola H. Ekblom P. Henke-Fahle S. Embryonic neurons as in vitro inducers of differentiation of nephrogenic mesenchyme. Devel. Biol. 132:271-281, 1989. 1988 Sariola H. Aufderheide E. Bernhard H. Henke-Fahle S. Dippold W. Ekblom P. Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions. Cell 54:235-245, 1988. Sariola H. Holm K. Henke-Fahle S. Early innervation of the metanephric kidney. Development 104:589-599, 1988. 1986 Sariola H. Viljanen T. Luosto R. Histological pattern and changes in extracellular matrix in aortic dissections. J. Clin. Pathol. 39:1074-1081, 1986. 1984 Sariola H. Timpl R. von der Mark K. Mayne R. Fitch JM. Linsenmayer TF. Ekblom P. Dual origin of glomerular basement membrane. Devel. Biol. 101:86-96, 1984. Sariola H. Kuusela P. Ekblom P. Cellular origin of fibronectin in interspecies hybrid kidneys. J. Cell Biol. 99:2099-2107, 1984. 1983 Sariola H. Ekblom P. Lehtonen E. Saxén L. Differentiation and vascularization of the metanephric kidney grafted on the chorioallantoic membrane. Devel. Biol. 96:427-435, 1983.
SELECTED Reviews, Chapters in Books, Editorials and Tutorials (in peer reviewed publications) 2005 Arighi E., Borrello M.G., Sariola H. RET tyrosine kinase signaling in development and cancer. Cytokine Growth Factor Rev. 16:441-67, 2005. 2003 Sariola, H., Sainio, K., Bard, J. The fates of the metanephric mesenchyme. In: The kidney. From normal development to congenital disease, pp. 181-193. Eds. P. Vice, A. Woolf, J. Bard. Academic Press, 2003 2002 Sariola, H. Nephron induction revisited: from caps to condensates. Curr. Opin. Nephol. Hypertens. 11:17-21, 2002 Sariola, H. Nephron induction. Nephrol. Dial. Transpl. 17:1-3, 2002 2001 Sariola, H. The neurotrophic factors in non-neuronal tissues. Cellul. Molec. Life Sci. 58:1061-1066, 2001 1999 Sariola H. Philipson L. Bridge over troubled waters. Nature Med. 5:22-23, 1999 1998 Sariola, H., Bard, J. Kidney development. In: Encyclopaedia of Life Sciences. MacMillan References Ltd., www.els.net, 1998 Sariola, H., Sainio, K. The cell lineages in kidney morphogenesis: their inductive interactions and signalling molecules. Biochem. & Cell Biol. 76:1009-1016, 1999 1997 Sariola, H., Sainio, K. The tip-top branching ureter bud. Curr. Op. Cell Biol. 9:877-884, 1997 1996 Sariola, H. Does the kidney express redundant or important molecules during nephrogenesis?. Exp. Nephrol. 4:70-76, 1996. 1994 Sariola H., Sainio K., Arumäe U., Saarma M. Neurotrophins and ciliary neurotrophic factor: their biology and pathology. Ann. Med. 26:355-363, 1994 1989 Sariola H. Holm-Sainio K. Henke-Fahle S. The effect of neuronal cells on kidney differentiation. Int. J. Devel. Biol. 33:149-55, 1989.
|
