Castrén group: Selected publications


Research People Selected publications

 

Castrén E, Hen, R (2013). Neuronal Plasticity and Antidepressant Effects.  Trends Neurosci. 36: 259-267.

Rantamäki T, Kemppainen S, Autio H, Stavén S, Koivisto H, Kojima M, Antila H, Miettinen PO, Kärkkäinen E,  Karpova N, Vesa L, Lindemann L, Hoener MC, Tanila H, Castrén E. (2013). The Impact of BDNF Gene Deficiency to the Memory Impairment and Brain Pathology of APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease. PLoS ONE 8(7): e68722.

Shulga A, Magalhaes A, Autio H, Plantman S, Di Lieto A, Nykjaer A, Carlstedt T, Risling M, Arumäe U, Castrén E, Rivera C (2012). The loop diuretic bumetanide blocks post-traumatic p75NTR upregulation and rescues injured neurons.  J Neurosci 32:1757-1770.

Maya-Vetencourt JF, Tiraboschi E, Greco D, Laura Restani L, Cerri C, Auvinen P, Maffei L and Castrén E  (2012). Experience-dependent NPAS4 expression mediates plasticity in adult visual cortex.  J. Physiol. 590: 4777-4787.

Karpova N, Pickenhagen A, Lindholm J, Tiraboschi E, Kulesskaya N, Ágústsdóttir A, Antila H, Popova D, Akamine Y, Bahi A, Sullivan R, Hen R, Drew LJ and Castrén E (2011). Fear Erasure in Mouse Requres Synergy Between Antidepressant Drug Treatment and Exposure Therapy. Science 334:1731-1734

Rantamäki T, Vesa L, Antila H, Di Lieto A, Tammela P, Schmitt A, Lesch K-P, Rios M, Castrén E (2011). Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade. PLoS One 6 (6): e20567.

Wu X and Castrén E (2009). Co-treatment with diazepam prevents the effects of fluoxetine on hippocampal neurogenesis. Biol. Psychiatry 66: 5-8

Sallert M., Rantamäki T., Vesikansa A., Anthoni H., Harju K., Yli-Kauhaluoma J., Taira T., Castrén E, Lauri SE (2009). BDNF controls activity-dependent maturation of CA1 synapses by down regulating tonic activation of presynaptic kainate receptors.  J Neurosci 29:11294 –11303.

Maya Vetencourt JF, Sale A, Viegi A, Baroncelli L, De Pasquale R, O’Leary OF, Castrén E and Maffei L (2008). The antidepressant fluoxetine restores plasticity in the adult visual cortex. Science 320: 385-388..

Sairanen M, Lucas G, Ernfors P, Castrén M, Castrén E (2005). BDNF and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation and survival in the adult dentate gyrus. J Neurosci 25: 1089-1094.

Castrén E (2005). Is mood chemistry? Nat. Rev. Neurosci. 6: 241-246

Saarelainen T, Hendolin P, Koponen E, Lucas G, MacDonald E, Agerman K, Haapasalo A, Nawa H,  Ernfors P, Aloyz R, Castrén E ( 2003). Activation of the trkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.  J. Neurosci 23 :349-357.