Publications from 2010 until present



Happonen LJ, Oksanen E, Liljeroos L, Goldman A, Kajander T & Butcher SJ (2013) The Structure of the NTPase That Powers DNA Packaging into Sulfolobus Turreted Icosahedral Virus 2. J Virol 87, 8388–8398.

Bhattacharjee A, Oeemig JS, Kolodziejczyk R, Meri T, Kajander T, Lehtinen MJ, Iwai H, Jokiranta TS & Goldman A (2013) Structural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferi. J Biol Chem 288, 18685–18695

Meri T, Amdahl H, Lehtinen MJ, Hyvärinen S, McDowell JV, Bhattacharjee A, Meri S, Marconi R, Goldman A & Jokiranta TS (2013) Microbes bind complement inhibitor factor H via a common site. PLoS Pathog 9, e1003308

Repo H, Kuokkanen E, Oksanen E, Goldman A & Heikinheimo P (2013) Is the Bovine lysosomal phospholipase B-like protein an amidase? Proteins in press


Mikula KM, Kolodziejczyk R, Goldman A. (2012) Yersinia infection tools-characterization of structure and function of adhesins. Front Cell Infect Microbiol. 2012;2:169. doi: 10.3389/fcimb.2012.00169. Epub 2013 Jan 8.

Kellosalo J, Kajander T, Honkanen R, Goldman A. (2012) Crystallization and preliminary X-ray analysis of membrane-bound pyrophosphatases. Mol Membr Biol. 2012 Aug 13.

Kellosalo J, Kajander T, Kogan K, Pokharel K, Goldman A. (2012) The structure and catalytic cycle of a sodium-pumping pyrophosphatase. Science. 2012 Jul 27;337(6093):473-6. doi: 10.1126/science.1222505.

Bhattacharjee A, Meri T, Kolodziejczyk R, Oeemig JS, Iwai H, Goldman A & Jokiranta TS (2012) Structural comparison of the two distinct microbial binding regions on host complement regulator factor H. IMMUNOLOGY 137, 156–156.

Bhattacharjee A, Strobel S, Kolodziejczyk R, Seeberger H, Hyvarinen S, Prohaszka Z, Goldman A, Jozsi M & Jokiranta S, T. (2012) Structural comparison of the C-terminal domains of factor H and CFHR-1 suggests explanation for the location of a major autoantibody epitope in autoimmune aHUS. IMMUNOBIOLOGY 217, 1221–1221.

Zhang H, Patana AS, Mackenzie PI, Ikushiro S, Goldman A, Finel M. (2012) Human UDP-glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal his-tag on glucuronidation kinetics. Drug Metab Dispos. 2012 Oct;40(10):1935-44.

Mikula KM, Leo JC, Łyskowski A, Kedracka-Krok S, Pirog A, Goldman A. (2012) The translocation domain in trimeric autotransporter adhesins is necessary and sufficient for trimerization and autotransportation. J Bacteriol. 2012 Feb;194(4):827-38.


Kajander T, Kuja-Panula J, Rauvala H, Goldman A.(2011) Crystal structure and role of glycans and dimerization in folding of neuronal leucine-rich repeat protein AMIGO-1.J Mol Biol. 2011 Nov 11;413(5):1001-15

Jurvansuu JM, Goldman A.(2011) Obesity risk gene TMEM18 encodes a sequence-specific DNA-binding protein. PLoS One. 2011;6(9):e25317

Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A. (2011) The structure of E. coli IgG-binding protein D suggests a general model for bending and binding in trimeric autotransporter adhesins. Structure. 2011 Jul 13;19(7):1021-30

Łyskowski A, Leo JC, Goldman A (2011) Structure and biology of trimeric autotransporter adhesins. Adv Exp Med Biol. 2011;715:143-58

Lyskowski A, Oeemig JS, Jaakkonen A, Rommi K, DiMaio F, Zhou D, Kajander T, Baker D, Wlodawer A, Goldman A, Iwaï H. (2011) Cloning, expression, purification, crystallization and preliminary X-ray diffraction data of the Pyrococcus horikoshii RadA intein. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt 5):623-6

Kajander T, Lehtinen MJ, Hyvärinen S, Bhattacharjee A, Leung E, Isenman DE, Meri S, Goldman A, Jokiranta TS. (2011) Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2897-902

Kaila VR, Oksanen E, Goldman A, Bloch DA, Verkhovsky MI, Sundholm D, Wikström M. (2011) A combined quantum chemical and crystallographic study on the oxidized binuclear center of cytochrome c oxidase. Biochim Biophys Acta. 2011 Jul;1807(7):769-78



Leo, J. C., Elovaara, H., Bihan, D., Kilpinen, S. K., Raynal, N., Farndale, R. W. & Goldman, A. (2010)   First analysis of a bacterial collagen-binding protein with collagen Toolkits: promiscuous binding of YadA to collagens may explain how YadA interferes with host processes.Infect. Immun. 78, 3226-36.

Tuominen, H., Salminen, A., Oksanen, E., Jämsen, J., Lipiäinen, O., Lehtiö, L., Magretova, N. N., Goldman, A., Baykov, A. A., and Lahti, R. (2010) Crystal structures of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with the inhibitor, AMP, and activator, diadenosine tetraphosphate, J. Mol. Biol. 398, 400-413.

Leppänen, V.-M., Prota, A. E., Jeltsch, M., Anisimov, A., Kalkkinen, N., Strandin, T., Lankinen, H., Goldman, A., Ballmer-Hofer, K., and Alitalo, K. (2010) Structural determinants of growth factor binding and specificity by VEGF-Receptor 2, Proc. Natl. Acad. Sci. U S A 107, 2425-2430.

Leo, J. C., and Goldman, A. (2010) Jacks of all trades? – probably not. The E. coli Eib proteins bind Fcs, Mol. Immunol. 47, 1870-1872.

Bhattacharjee, A., Lehtinen, M. J., Kajander, T., Goldman, A. & Jokiranta, S. T.(2010) Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d, Mol. Immunol. 47, 1689-1691

Ora, A., Oksanen, E., Kajander, T., Goldman, A., and Butcher, S. J. (2010) Preliminary crystallographic analysis of mouse peroxiredoxin II with significant pseudosymmetry, Acta Crystallogr. F 66, 357-360.