Natural organic compounds analysis unit (NOCA)

NOCA Unit situates at Viikki campus at the Faculty of Agriculture and Forestry,  Department of Food and Environmental Sciences in two locations: Biocenter 1 and D-building (see picture and  map).

NOCA Unit co-operates with research groups from Faculty of Agriculture and Forestry, Faculty of Pharmacy and with other domestic and international research groups on the field of analysis and structural characterisation of small biomolecules.

NOCA Unit is specialised to analyze organic compounds from nature. These are microbial peptides and other secondary metabolites, biomolecules in food and in other biomaterials. Special knowledge of biological sample preparation and isolation, purification and characterisation of biomolecucules situates in NOCA Unit.

Services of NOCA Unit

Operation principle of the NOCA Unit:

As a general principle everybody are welcome to use the equipments of NOCA Unit or purchase analyses from the NOCA Unit. First a person have to agree with the operator and/or person in charge about the usage and usage times of the equipments. Operators familiarize the new users (students, researchers) before they can start the independent use of the equipments. Technical staff and operators are responsible of the maintenance of the analytical hardware.  Researchers or other users are primarily responsible of the analysis and interpretation of the obtained results.  In case of academic collaboration and in non-academic contract research all kind of arrangements are possible.

Analysis available

In D-building, available analysis include:

    • Analysis and characterisation of bioactive compounds
      • vitamins
      • lipids (polymers, neutral lipid classes, fatty acids)
      • lipid oxidation
      • plant sterols, sterol oxides
      • plant pigments, phenolics.
    • Antioxidant activities and protein oxidation products
        
    • Analysis of monosaccharides and polymers
      • Characterization of molecular size and molecular mass distribution in aqueous and organic system
      • Separation of oligosaccharides, peptides and proteins
      • Characterization of polymers and particles from biological origin.
    • Determination of elements

    In Biocenter 1 (Microbiology), we are specialised in qualitative analysis of microbial secondary metabolites:   

    • Identification of known and novel cyclic peptides
    • Chiral analysis of amino acids.
    Instruments in D Building >>
  • HPLC High Performance Liquid Chromatograph
  • UHPLC UltraHigh Performance Liquid Chromatograph
  • HPSEC High Performance Size Exclusion Chromatograph
  • HPAEC-PAD High Performance Anion Exchange Chromatograph with Pulse Amperometric detector
  • LC-MS High Definition Mass Spectrometry
  • LC-MS Liquid Chromatograph - Mass Spectrometer
  • GC Gas Chromatograph
  • GC-MS Gas Chromatograph - Mass Spectrometer
  • CE Capillary Electrophoresis apparatus
  • AsFFFF Asymmetric Flow Field – Flow Fractionation apparatus
  • ICP-MS Inductively Coupled Plasma Mass Spectrometer
  • ICP-OES Inductively Coupled Plasma Optical Emission Spectrometer
  • FT-IR Fourier Transform Infrared Spectrometer
    Instruments in Biocenter 1 >>

    Prices

    HPLC-ITMS analysis

    Academic contracts: 35 € per sample run (in Biocenter 1).

    Academic collaboration / non-academic contract research: request a quote
    Academic collaboration is the first option.
    Each case is evaluated individually.

    People and contact information

    D Building

    P.O. Box 27 (Latokartanonkaari 11)
    FI-00014 University of Helsinki, Finland

    Velimatti Ollilainen, PhD, Docent
    +358 (0) 2941 58227
    velimatti.ollilainen (at) helsinki.fi

    Päivi Tuomainen, PhD, Docent
    +358 (0) 2941 58407
    paivi.tuomainen (at) helsinki.fi

    Miikka Olin, Technician
    +358 (0) 2941 58675
    miikka olin (at) helsinki.fi

     

    Biocenter 1
    P.O. Box 56 (Viikinkaari 9)
    FI-00014 University of Helsinki, Finland

    Kaarina Sivonen Professor of Applied Microbiology
    +358 (0) 2941 59600
    kaarina.sivonen (at) helsinki.fi
    http://www.helsinki.fi/food-and-environment/research/groups/cyanobacteria.html

    Jouni Jokela, PhD, Docent
    +358 (0) 2941 59296, +358 (0) 40 548 4987
    jouni.jokela (at) helsinki.fi

    Matti Wahlsten, Operator
    +358 (0) 2941 59296
    matti.wahlsten (at) helsinki.fi


    Buildings on Viikki Campus http://www.helsinki.fi/viikki/english/buildings.html